ID I1NQE8_ORYGL Unreviewed; 522 AA.
AC I1NQE8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Oryza glaberrima (African rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA01G0208800.1, ECO:0000313|Proteomes:UP000007306};
RN [1] {ECO:0000313|Proteomes:UP000007306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA Zuccolo A.;
RT "The complete genome of Oryza glaberrima.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORGLA01G0208800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR AlphaFoldDB; I1NQE8; -.
DR MEROPS; A01.020; -.
DR EnsemblPlants; ORGLA01G0208800.1; ORGLA01G0208800.1; ORGLA01G0208800.
DR Gramene; ORGLA01G0208800.1; ORGLA01G0208800.1; ORGLA01G0208800.
DR eggNOG; KOG1339; Eukaryota.
DR HOGENOM; CLU_013253_3_1_1; -.
DR OMA; IGELWIL; -.
DR Proteomes; UP000007306; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06098; phytepsin; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR Gene3D; 1.10.225.10; Saposin-like; 1.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR033869; Phytepsin.
DR InterPro; IPR007856; SapB_1.
DR InterPro; IPR008138; SapB_2.
DR InterPro; IPR011001; Saposin-like.
DR InterPro; IPR008139; SaposinB_dom.
DR PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR47966:SF4; OS01G0663400 PROTEIN; 1.
DR Pfam; PF00026; Asp; 1.
DR Pfam; PF05184; SapB_1; 1.
DR Pfam; PF03489; SapB_2; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF47862; Saposin; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 2.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
DR PROSITE; PS50015; SAP_B; 2.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750,
KW ECO:0000256|RuleBase:RU000454};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR601461-2};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000454};
KW Protease {ECO:0000256|RuleBase:RU000454}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..522
FT /note="Peptidase A1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003648155"
FT DOMAIN 98..519
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT DOMAIN 328..368
FT /note="Saposin B-type"
FT /evidence="ECO:0000259|PROSITE:PS50015"
FT DOMAIN 392..433
FT /note="Saposin B-type"
FT /evidence="ECO:0000259|PROSITE:PS50015"
FT ACT_SITE 116
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 303
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT DISULFID 129..135
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
FT DISULFID 294..298
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
SQ SEQUENCE 522 AA; 55811 MW; C5CE32C69FBFB15D CRC64;
MGTRRVGLLL LVLLAAVLLQ PLLAAAAAEG VVRIALKKRQ VDETGRVGGH LAGEDAQRLL
ARRHGFLTND AARAASRKAR AEAEGDIVAL KNYLNAQYYG EIAIGTPPQM FTVIFDTGSS
NLWVPSSKCH LSIACYFHSR YKAGQSSTYK KNGKPASIHY GTGAISGYFS QDSVKVGDVA
VKNQDFIEAT REPSITFMVA KFDGILGLGF KEISVGNAVP IWYNMVRQGL VVDPVFSFWF
NRHADEGQGG EIVFGGIDPN HYKGNHTYVP VTRKGYWQFN MGDVLIGGNS TGFCAAGCAA
IADSGTSLLT GPTAIITQIN EKIGATGVVS QECKAVVSQY GQQILDQLRA ETKPAKVCSS
VGLCTFDGTH GVSAGIRSVV DDEVGKSSGP FSSAMCNACE TAVVWMHTQL AQNQTQDLVL
QYIDQLCDRL PSPMGESSVD CSSLASMPDI AFTIGGNKFV LKPEQYILKV GEGTATQCIS
GFTAMDIPPP RGPLWILGDV FMGAYHTVFD YGNLKVGFAE AA
//
