ID   I1NRU6_ORYGL            Unreviewed;      1044 AA.
AC   I1NRU6;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
OS   Oryza glaberrima (African rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA01G0258600.1, ECO:0000313|Proteomes:UP000007306};
RN   [1] {ECO:0000313|Proteomes:UP000007306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA   Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA   Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA   Zuccolo A.;
RT   "The complete genome of Oryza glaberrima.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORGLA01G0258600.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- FUNCTION: Possesses non-specific lipolytic acyl hydrolase (LAH)
CC       activity. Hydrolyzes phospholipids as well as galactolipids. May play a
CC       role in disease resistance. {ECO:0000256|ARBA:ARBA00025642}.
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DR   STRING; 4538.I1NRU6; -.
DR   EnsemblPlants; ORGLA01G0258600.1; ORGLA01G0258600.1; ORGLA01G0258600.
DR   Gramene; ORGLA01G0258600.1; ORGLA01G0258600.1; ORGLA01G0258600.
DR   eggNOG; KOG2214; Eukaryota.
DR   HOGENOM; CLU_013822_0_0_1; -.
DR   Proteomes; UP000007306; Unassembled WGS sequence.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07231; Pat_SDP1-like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR021771; Triacylglycerol_lipase_N.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR   Pfam; PF11815; DUF3336; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098}.
FT   DOMAIN          234..437
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   REGION          626..663
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          725..752
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          814..853
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        834..853
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1044 AA;  115208 MW;  46527389478BB44B CRC64;
     MDAISSEAPV GVFAIGPSTA LGRALALRVL LCGSLGRLRH RLAAALRAAL PVAAGWLHPR
     XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXQSAYRRK FWRNMMRAAL TYEEWAHAAR
     MLDRETPRRA TDADLYDEEL VRNKLRELRH RRQEGSLRDI VFCMRADLLR NLGNMCNSEL
     HKGRLQVPKL IKEYIEEVST QLKMVCNSDS DDLPLEEKLA FMHETRHAFG RTALLLSGGA
     SLGCFHVGVV KTLVEHKLLP RIISGSSVGS IMCSIVATRS WPELESFFEE WHSLKFFDQM
     GGIFPVVKRI LTHGAVHDIR HLQMLLRNLT SNLTFQEAYD MTGRILVVTV CSPRKHEPPR
     CLNYLTSPHV LIWSAVTASC AFPGLFEAQE LMAKDRFGET VPFHAPFLLG LEERVGATTR
     RWRDGSLESD LPMKQLKELF NVNHFIVSQA NPHIAPLLRL KEIIRAYGGS FAAKLAELAE
     MEVKHRCNQI LELGFPLGGI AKLFAQDWEG DVTVVMPATL AQYSKIIQNP SYAELQKAAN
     QGRRCTWEKL SAIRANCAIE LVLDECVALL NHMRRLKRSA ERAAASQGHG PTIRLCPSRR
     IPSWNLIARE NSSGSLEEEF LISPRTNHHA DGGIAGPSNK NHHVQQNVHD GSDSESESID
     LNSWTRSGGP LMRTASANKF VSFVQNLEID TEFRTISSRE DRTDVVTPNA NFLVSQAIGR
     ESVDNSAMPI TPDRSLGNSG YDPHDSNVPR SPFGCSTSIM VSEGDLLQPE KIENGILFNV
     VRRDTLLTPT GGVELQGTSQ EPDVETIQTE CLDDASDDDD VGLNAGDEAA IDPRANMSSQ
     NTQHQGSSLE NINLSSSVDC EAETITSKSE GSSLFDIGME IRPTILSTES SVYERSSAKI
     GLRTVHAEFI SNPGAGKGEV DSGAANKEFS YFSQTADTVI FSESCETGQH HEVNVEALTS
     YPVSVLEDDR SGGFNLSEIM ATTFIAEADA PISRRDEVEQ HNGSPVETFL DTETVQAGPC
     SSTLEGNNTN NSEEMQVVCT SGTN
//