ID   I1NW02_ORYGL            Unreviewed;       759 AA.
AC   I1NW02;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Peptidase M28 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Oryza glaberrima (African rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA01G0404200.1, ECO:0000313|Proteomes:UP000007306};
RN   [1] {ECO:0000313|Proteomes:UP000007306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA   Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA   Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA   Zuccolo A.;
RT   "The complete genome of Oryza glaberrima.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORGLA01G0404200.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC       {ECO:0000256|ARBA:ARBA00005634}.
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DR   AlphaFoldDB; I1NW02; -.
DR   STRING; 4538.I1NW02; -.
DR   EnsemblPlants; ORGLA01G0404200.1; ORGLA01G0404200.1; ORGLA01G0404200.
DR   Gramene; ORGLA01G0404200.1; ORGLA01G0404200.1; ORGLA01G0404200.
DR   eggNOG; KOG2195; Eukaryota.
DR   HOGENOM; CLU_005688_3_1_1; -.
DR   OMA; TEWMEEY; -.
DR   Proteomes; UP000007306; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd08022; M28_PSMA_like; 1.
DR   CDD; cd02121; PA_GCPII_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR039373; Peptidase_M28B.
DR   InterPro; IPR007365; TFR-like_dimer_dom.
DR   InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR   PANTHER; PTHR10404:SF67; GLUTAMATE CARBOXYPEPTIDASE 2; 1.
DR   PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   Pfam; PF04253; TFR_dimer; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        38..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          176..263
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          363..567
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   DOMAIN          628..754
FT                   /note="Transferrin receptor-like dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF04253"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   759 AA;  82603 MW;  9BBD5ACF61E9B8A5 CRC64;
     MSRHGKPQQR QPLILPDAAP MGGGDGGRGD AATRRRRFVA FLAISVALVA SYHHLAPAPA
     SRYHALFLSL GNNDTAAAHL RALTLRPHVA GTEANAVAAE YVRAALSSFS FPTRVTPYSV
     LLSYPIHRSL SLSVPGRAAA FNFALVQETY PGDPYSEAAA EVIPTYFAYS ASGSVAAEVV
     YANYGNTKDY EYLASRGVDV AGKVALVRYG NLHCEDMVRN ARAAGAAAAI VYTDAKDFGG
     AGAKGKRKWF PDARWLPPTG VQVGTLYYGN GDPTTPLWPS CAAGEDCERL SQGELDGSAA
     MPSIPALPVS ARDGETILKA MGGDAAPTEW QGGEGAPMYR LGPGPAVLNL TYIGNDTLAT
     IENVFAVIEG KEEPDRYVII GNHRDAWTFG AVDPNSGTAA MLEIAERLSK LEKKGWRPRR
     TIIVCSWDAE EFALIGSTEW VEDNMDMLAS RAIAYLNVDI TVFGPGGFRP RATPQLDQLI
     KEASKMVQDP DDPSQTLYDT MIRHHPPIDR VAGAGTDFAA FLQYIGVPSL DMSYGTISAA
     VTPLASTNII ALAVEDYPVY HSLYDDYVWM ERFGDPLFHR HVALASVWGL IALRLADDEI
     LPLNYVSYAS ELEKCTKLVE GGCTGCPVSF APLHKSIDQL RKAANKIHKE KMMLQAENWS
     LKTRAYTVKV RDINDRLMMA ERGFINREGL DGRPWYKHMI YASSDQDDWG TKAFPGIVSA
     IDKANKLNTT ESWQLLQHEI YRAARAVSKA SAVLDGRLT
//