ID I1P5W9_ORYGL Unreviewed; 1076 AA.
AC I1P5W9;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
OS Oryza glaberrima (African rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA02G0337500.1, ECO:0000313|Proteomes:UP000007306};
RN [1] {ECO:0000313|Proteomes:UP000007306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA Zuccolo A.;
RT "The complete genome of Oryza glaberrima.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORGLA02G0337500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC ECO:0000256|RuleBase:RU004914}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU004914}.
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DR AlphaFoldDB; I1P5W9; -.
DR STRING; 4538.I1P5W9; -.
DR EnsemblPlants; ORGLA02G0337500.1; ORGLA02G0337500.1; ORGLA02G0337500.
DR Gramene; ORGLA02G0337500.1; ORGLA02G0337500.1; ORGLA02G0337500.
DR eggNOG; KOG1347; Eukaryota.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_287068_0_0_1; -.
DR OMA; TKTPVFF; -.
DR Proteomes; UP000007306; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR044644; DinF-like.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR002885; Pentatricopeptide_rpt.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00797; matE; 1.
DR NCBIfam; TIGR00756; PPR; 4.
DR PANTHER; PTHR42893:SF18; PROTEIN DETOXIFICATION; 1.
DR PANTHER; PTHR42893; PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF01554; MatE; 1.
DR Pfam; PF01535; PPR; 6.
DR PROSITE; PS51375; PPR; 4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU004914};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT TRANSMEM 780..803
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 824..845
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 851..873
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 917..941
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 961..988
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 1000..1018
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 1030..1049
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT REPEAT 193..227
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REPEAT 363..393
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REPEAT 394..428
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REPEAT 495..529
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
SQ SEQUENCE 1076 AA; 113984 MW; A38DF4101D55C6A5 CRC64;
MATAGVVVEE AVRRYAGGKP AALLPALLGL LSRQQPSSGW ARALASQLHA DVAKRPLSAA
ASNSLLCYYL RSSRLDLALH HLRCRSTPRD SLTYNTLLNH LPASSSSSTT FRLFRFAMRH
AHAAFHPNVA SLLSLLRASS SYSDHFLHMI HAYLLKTPAS IHTPVANSLL SLYATLGDFA
SAAILFGEMP DRDVASWTSM IGACLGSGYA DQALRLFREM LADGALQPDG VVAVVVLRAC
AMLEDVRAGA SVHAVATRRG LQGDLFVDNS LVDMYAKCLD LRSARKVFDL IAVKNVVSWN
TMLSGLVHAG SYPEALHLLA LQIGVVGDET TLAVLLQLCK KKRLGGQAAR SVHGAAIRRR
LLSMALLNAL LDAYGKCGLV EDVLRLFQGM RERNVITWST VIAACAHNGW PHAAMACFVA
MLETGERPNS ITVLSLVEAC GSCAEMWASR RAHGVAVRSG LGFELAVGNA LVHMYGKCGE
LGASARVFDT MPVKDVFTWN SMIGALGMNG RARDALALLH RMEAEGDEVR PNGVTMLAAL
WACAHGGLVE EGIGCLESMA RQSLQPRVEH VSCVVDMLAR AGDLDGAAEI VRRSSGGGSP
AAWSALLSAC RRRGDGGGGE VGRSAAARVL ELEPGKSAGY LMSMGMGLGK GWAAGMRWAM
REKGVKVESG HSVVQHAGGS ERDLRPGGVR NELILLALPA VLGQAIDPLA QLMETAYIGR
LGALELASAG IGVSVFNIVS KIFNIPLLSI ATSFVAEDIS KNASKHSSSG KLELSSVSSA
LVLAAGIGTI EALALFLGSG LFLKLMGVSP ASPMHKPAKL FLSLRALGAP ANVIMLAVQG
IFRGFKDTKT PVFFIGLGNL SAVVLLPLLI YVFRLGITGA AISTVASQYV DQLVIDRAFI
HGPCPFCPLM NGLFRELLFS ILFRGGMLLG RTLSILLTMT IGTSMAARQG PTAMAAHQIC
LQVWLAVSLL ADALAVSAQA MIASSYAILD YKRVQKIAMF ALQFVCASQP INALAFIFDG
LHYGVSDFDY VAQATIAVGV MSSLVLLYAP SVFGLAGVWA GLTTLMGLRM ASGILR
//
