ID I1PNM2_ORYGL Unreviewed; 884 AA.
AC I1PNM2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038};
DE EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};
OS Oryza glaberrima (African rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA04G0179100.1, ECO:0000313|Proteomes:UP000007306};
RN [1] {ECO:0000313|Proteomes:UP000007306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA Zuccolo A.;
RT "The complete genome of Oryza glaberrima.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORGLA04G0179100.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|RuleBase:RU365038};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906, ECO:0000256|RuleBase:RU365038}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU365038}.
CC -!- SIMILARITY: Belongs to the BRE1 family. {ECO:0000256|ARBA:ARBA00005555,
CC ECO:0000256|RuleBase:RU365038}.
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DR AlphaFoldDB; I1PNM2; -.
DR STRING; 4538.I1PNM2; -.
DR EnsemblPlants; ORGLA04G0179100.1; ORGLA04G0179100.1; ORGLA04G0179100.
DR Gramene; ORGLA04G0179100.1; ORGLA04G0179100.1; ORGLA04G0179100.
DR eggNOG; KOG0978; Eukaryota.
DR HOGENOM; CLU_002640_1_0_1; -.
DR OMA; THIEIMT; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000007306; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:EnsemblPlants.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0051301; P:cell division; IEA:EnsemblPlants.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IEA:EnsemblPlants.
DR GO; GO:0045087; P:innate immune response; IEA:EnsemblPlants.
DR GO; GO:0009965; P:leaf morphogenesis; IEA:EnsemblPlants.
DR GO; GO:0051781; P:positive regulation of cell division; IEA:EnsemblPlants.
DR GO; GO:0006513; P:protein monoubiquitination; IEA:EnsemblPlants.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:EnsemblPlants.
DR GO; GO:0010162; P:seed dormancy process; IEA:EnsemblPlants.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IEA:EnsemblPlants.
DR CDD; cd16499; RING-HC_Bre1-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013956; E3_ubiquit_lig_Bre1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23163:SF0; E3 UBIQUITIN-PROTEIN LIGASE BRE1; 1.
DR PANTHER; PTHR23163; RING FINGER PROTEIN-RELATED; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853,
KW ECO:0000256|RuleBase:RU365038};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU365038};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU365038}; Nucleus {ECO:0000256|RuleBase:RU365038};
KW Transferase {ECO:0000256|RuleBase:RU365038};
KW Ubl conjugation pathway {ECO:0000256|RuleBase:RU365038};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU365038};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 832..871
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 107..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 51..78
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 216..278
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 422..449
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 473..507
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 698..732
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 107..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 884 AA; 100426 MW; 8A157D16EC660B23 CRC64;
MGSTGEPDRK RRLSSSVAPG GGAPVSPAKR LAVAPTSEDK KLDFTVLKYK NQKLSEQLEA
HKFEYRALEN KFAGLKEKQR THNETLSLVN SSWEQLVADL KSRSFCKSGS PNSSPGSGHN
NVQKDGTCAP IERDTLRSLV ESGATESSGC LPGCHLGSDA PPLHLSTANA LGDIFFPSSD
LLQANEECAL AALTKLPEND RSKQLQSTSS NLLSSLNNVV QALSNLQLKH KQLAEDYQNQ
RDSSARKRAE HRRLKEELAS AASELEETNY KLAALKAQRD NTQGARIPYP TLGNKNMPED
KVRDKQREMQ DLEATHKELS ELISKRLVEI KRLHEERIEI LNKIATFQNI LMDFKSIRSS
KAFQLVNDRL QKSQAELDHY QTLLEKLQVD KDKFVWQERQ FNLKVDLAEI PERVSTYCES
SIADLKKDIQ KLRDEKNMLI LKLEEASREP GRNQVITKFK ALVSSIPREM GAMQSEMTKH
KEASLELNSL RAEVHSLSRI LSRKERDNEE ASCRSARAGS DITQLQSVIS DLKQTNKELK
LFADMYKRES TDSREIMESR DREFLEWAHV HALKSSLDES KLEQRVKAAN EAEAITQQRL
ATAEAEIAES GQKLGTSRKD LVSLSHMLKS KQEECEAYRV EVECIGQAYE DIQAQNQQLL
QQIIERDDDN TKIFMEGVKA KQTQDALHLE TYSLRRNLQQ ESSLMDLYNQ KIVSLEDQLK
MWSDRVGKLQ EDGWQQSVSL SNYQRKLVDV HRDAQKLMQS LDGIQANVGS SRLEVADLLI
ELEKERFSKK RIEDDLEVMS RKASSLRAKA RESAVLEKLR HEVKEYRGIL KCGICHDRQK
EVVITKCYHL FCNQCIQKSL GNRQRRCPSC SLSFGANDVK PIYI
//
