ID   I1QCK4_ORYGL            Unreviewed;       253 AA.
AC   I1QCK4;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=dTMP kinase {ECO:0000256|ARBA:ARBA00012980};
DE            EC=2.7.4.9 {ECO:0000256|ARBA:ARBA00012980};
OS   Oryza glaberrima (African rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA07G0184600.1, ECO:0000313|Proteomes:UP000007306};
RN   [1] {ECO:0000313|Proteomes:UP000007306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA   Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA   Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA   Zuccolo A.;
RT   "The complete genome of Oryza glaberrima.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORGLA07G0184600.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- PATHWAY: Pyrimidine metabolism; dTTP biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004992}.
CC   -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC       {ECO:0000256|ARBA:ARBA00009776}.
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DR   AlphaFoldDB; I1QCK4; -.
DR   SMR; I1QCK4; -.
DR   STRING; 4538.I1QCK4; -.
DR   EnsemblPlants; ORGLA07G0184600.1; ORGLA07G0184600.1; ORGLA07G0184600.
DR   Gramene; ORGLA07G0184600.1; ORGLA07G0184600.1; ORGLA07G0184600.
DR   eggNOG; KOG3327; Eukaryota.
DR   HOGENOM; CLU_049131_3_3_1; -.
DR   OMA; CRAPDVG; -.
DR   Proteomes; UP000007306; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:EnsemblPlants.
DR   GO; GO:0005654; C:nucleoplasm; IEA:EnsemblPlants.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004798; F:thymidylate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR   CDD; cd01672; TMPK; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   HAMAP; MF_00165; Thymidylate_kinase; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039430; Thymidylate_kin-like_dom.
DR   InterPro; IPR018095; Thymidylate_kin_CS.
DR   InterPro; IPR018094; Thymidylate_kinase.
DR   NCBIfam; TIGR00041; DTMP_kinase; 1.
DR   PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR   PANTHER; PTHR10344:SF1; THYMIDYLATE KINASE; 1.
DR   Pfam; PF02223; Thymidylate_kin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS01331; THYMIDYLATE_KINASE; 1.
PE   3: Inferred from homology;
FT   DOMAIN          56..231
FT                   /note="Thymidylate kinase-like"
FT                   /evidence="ECO:0000259|Pfam:PF02223"
SQ   SEQUENCE   253 AA;  27657 MW;  C0754907E834E58F CRC64;
     MTALACLAGK AISWSSGVKA AAGCGLGLLP QWRGVFRSVR MESGSSQGGR GALIVLEGLD
     RSGKSSQCAR LLSFLQGKGC QAEGWRFPDR GTSVGQMISA YLANESELDD RTIHLLFSAN
     RWEKRALMER KLLGGTTLIV DRYSYSGVAF SAAKGLDIEW CKAPENGLIA PDLVVYLDVQ
     PEKAAERGGY GGERYEKIEF QKKVGEHYHS LRDSTWKVVD GSLPMEVVEE QLKELAMSCI
     LECQSKQLAS LAW
//