ID   I1VB11_9CRUS            Unreviewed;       224 AA.
AC   I1VB11;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Caspase 8 {ECO:0000313|EMBL:AFI39975.1};
DE   Flags: Fragment;
OS   Daphnia parvula.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC   Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX   NCBI_TaxID=132684 {ECO:0000313|EMBL:AFI39975.1};
RN   [1] {ECO:0000313|EMBL:AFI39975.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=A60 {ECO:0000313|EMBL:AFI39975.1};
RX   PubMed=22577801; DOI=10.1186/1471-2148-12-63;
RA   McTaggart S.J., Obbard D.J., Conlon C., Little T.J.;
RT   "Immune genes undergo more adaptive evolution than non-immune system genes
RT   in Daphnia pulex.";
RL   BMC Evol. Biol. 12:63-63(2012).
CC   -!- SIMILARITY: Belongs to the peptidase C14A family.
CC       {ECO:0000256|ARBA:ARBA00010134, ECO:0000256|RuleBase:RU003971}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JQ856629; AFI39975.1; -; mRNA.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   InterPro; IPR002138; Pept_C14_p10.
DR   InterPro; IPR001309; Pept_C14_p20.
DR   InterPro; IPR015917; Pept_C14A.
DR   PANTHER; PTHR10454:SF245; APOPTOTIC CYSTEINE PROTEASE, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR10454; CASPASE; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   PRINTS; PR00376; IL1BCENZYME.
DR   SMART; SM00115; CASc; 1.
DR   SUPFAM; SSF52129; Caspase-like; 1.
DR   PROSITE; PS50207; CASPASE_P10; 1.
DR   PROSITE; PS50208; CASPASE_P20; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          10..130
FT                   /note="Caspase family p20"
FT                   /evidence="ECO:0000259|PROSITE:PS50208"
FT   DOMAIN          165..201
FT                   /note="Caspase family p10"
FT                   /evidence="ECO:0000259|PROSITE:PS50207"
FT   REGION          133..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AFI39975.1"
FT   NON_TER         224
FT                   /evidence="ECO:0000313|EMBL:AFI39975.1"
SQ   SEQUENCE   224 AA;  25152 MW;  D9033CE3BC382B39 CRC64;
     YKLYDLPEIK PGLCVIFNQE IFDNKGDNRP GTEKDREALI BVFKDFGFEV EPHDNLKAQQ
     LCDEIINLGE RDFSKYACLV VCILSHGDEG TVYGTEGNQV LIEDAKKQFN NPTLSGKPKI
     WIIQACQGPL EQGDYEKSTP TLEPTKLGPT IQANLPNQPP DIPRPPVSDI LDIRSTVPGN
     VCYRSTSTGS IFIKNLCKQL RTTFLNEGET SNRHLEDLLK MVQK
//