ID I1XHC0_METNJ Unreviewed; 550 AA.
AC I1XHC0;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=BCCT transporter {ECO:0000313|EMBL:AUZ83913.1};
DE SubName: Full=High-affinity choline uptake protein BetT {ECO:0000313|EMBL:AFI83789.1};
GN OrderedLocusNames=Q7A_947 {ECO:0000313|EMBL:AFI83789.1};
GN ORFNames=CDW43_04710 {ECO:0000313|EMBL:AUZ83913.1};
OS Methylophaga nitratireducenticrescens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=754476 {ECO:0000313|EMBL:AFI83789.1, ECO:0000313|Proteomes:UP000009144};
RN [1] {ECO:0000313|EMBL:AFI83789.1, ECO:0000313|Proteomes:UP000009144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM1 {ECO:0000313|EMBL:AFI83789.1,
RC ECO:0000313|Proteomes:UP000009144};
RX PubMed=22815445; DOI=10.1128/JB.00726-12;
RA Villeneuve C., Martineau C., Mauffrey F., Villemur R.;
RT "Complete genome sequences of Methylophaga sp. strain JAM1 and Methylophaga
RT sp. strain JAM7.";
RL J. Bacteriol. 194:4126-4127(2012).
RN [2] {ECO:0000313|EMBL:AFI83789.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JAM1 {ECO:0000313|EMBL:AFI83789.1};
RX PubMed=23148104; DOI=10.1099/ijs.0.044545-0;
RA Villeneuve C., Martineau C., Mauffrey F., Villemur R.;
RT "Methylophaga nitratireducenticrescens sp. nov. and Methylophaga frappieri
RT sp. nov., isolated from the biofilm of the methanol-fed denitrification
RT system treating the seawater at the Montreal Biodome.";
RL Int. J. Syst. Evol. Microbiol. 63:2216-2222(2013).
RN [3] {ECO:0000313|EMBL:AFI83789.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JAM1 {ECO:0000313|EMBL:AFI83789.1};
RA Villeneuve C., Villemur R.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AUZ83913.1, ECO:0000313|Proteomes:UP000238402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GP59 {ECO:0000313|EMBL:AUZ83913.1,
RC ECO:0000313|Proteomes:UP000238402};
RA Villemur R.;
RT "The sequence of the genome of Methylophaga nitratireducenticrescens GP59
RT and its two plasmids.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000256|ARBA:ARBA00005658}.
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DR EMBL; CP003390; AFI83789.1; -; Genomic_DNA.
DR EMBL; CP021973; AUZ83913.1; -; Genomic_DNA.
DR RefSeq; WP_014706164.1; NZ_CP021973.1.
DR AlphaFoldDB; I1XHC0; -.
DR STRING; 754476.Q7A_947; -.
DR KEGG; mej:Q7A_947; -.
DR PATRIC; fig|754476.3.peg.934; -.
DR eggNOG; COG1292; Bacteria.
DR HOGENOM; CLU_010118_5_2_6; -.
DR OrthoDB; 9775735at2; -.
DR Proteomes; UP000009144; Chromosome.
DR Proteomes; UP000238402; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR000060; BCCT_transptr.
DR NCBIfam; TIGR00842; bcct; 1.
DR PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF02028; BCCT; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 58791 MW; 843BB4E077918F31 CRC64;
MSSQADNSAE PQSAGVRAPN GATNLIDTDY QIGQDNYRAK HFGITVDLHG VVFIFSAIVV
LAFVFLSLAL PVQSTTIFEA CKNWINTNMS WFFLLSANIF VVLCLGLIIS PLGSIRIGGV
EAKPDFSRLS WFSMLFAAGM GIGLVFYGVS EPLSHYNSAF GGTSVGADGL RTDWAPLGGA
AGDPEAARQL GMAATIFHWG LHPWAIYAIV ALSLAIFSFN KGLPLTVRSI FYPILGERIW
GWPGHLIDIL AVFATLFGLA TSLGLGAQQA ASGLDYLFGI GDGNVVLVLL IAAITAVAIV
SIVAGVDKGV KRLSEINMIL AFVLLLFVVF VGPTLLIFSN FFSNLSSYLT ELPALSNPFG
REDANFSQGW TTFYWAWWIS WSPFVGMFIA RVSRGRTVRD FLTSVLLIPS IVSVFWMTAF
GTNAISQLQS GFDGVVSADL PLKLFVMLEQ LPLAEITSFI GIILVIVFFI TSSDSGSLVI
DTITAGGKID APKPQRVFWG VIEGAIAVAL LLGGGLAALQ AAAISAGLPF TLVLLVGCYA
IVRGLMTEPR
//
