ID I2AFZ7_9MYCO Unreviewed; 369 AA.
AC I2AFZ7;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=Peptidase, M24 family protein {ECO:0000313|EMBL:AFJ36221.1};
GN ORFNames=W7S_16300 {ECO:0000313|EMBL:AFJ36221.1};
OS Mycobacterium sp. MOTT36Y.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1168287 {ECO:0000313|EMBL:AFJ36221.1, ECO:0000313|Proteomes:UP000002868};
RN [1] {ECO:0000313|EMBL:AFJ36221.1, ECO:0000313|Proteomes:UP000002868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MOTT36Y {ECO:0000313|EMBL:AFJ36221.1,
RC ECO:0000313|Proteomes:UP000002868};
RX PubMed=22815454; DOI=10.1128/JB.00752-12;
RA Kim B.J., Choi B.S., Choi I.Y., Lee J.H., Chun J., Hong S.H., Kook Y.H.,
RA Kim B.J.;
RT "Complete genome sequence of Mycobacterium intracellulare clinical strain
RT MOTT-36Y, belonging to the INT5 genotype.";
RL J. Bacteriol. 194:4141-4142(2012).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|RuleBase:RU000590}.
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DR EMBL; CP003491; AFJ36221.1; -; Genomic_DNA.
DR RefSeq; WP_008258234.1; NC_017904.1.
DR AlphaFoldDB; I2AFZ7; -.
DR KEGG; mmm:W7S_16300; -.
DR PATRIC; fig|1168287.3.peg.3312; -.
DR HOGENOM; CLU_017266_4_0_11; -.
DR Proteomes; UP000002868; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01092; APP-like; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF8; CYTOPLASMIC PEPTIDASE PEPQ-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590}.
FT DOMAIN 6..136
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 144..347
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 369 AA; 38934 MW; B214CCFCD9B5E8BF CRC64;
MTHSQRRDRL RARLQTSGLD ALLVTDLVNV RYLSGFTGSN GALLVFADDR SPLLATDGRY
RTQAAEQAPD LEVAIERVLG RYLVGQAAAA GARKLGFESN VVTVDGFDAL TGELNDRKAP
TELVKAAGTV EALREVKDAG EVALLRLACE AADAALTDLV ARGGLRPGRT EREVSRELEA
LMLDHGADAI SFETIVAAGP NSAIPHHRPT DAALAAGDFV KIDFGALVGG YHSDMTRTFV
LGKAADWQLE IYQLVADSQR AGREALRAGA DLRGVDAAAR QVIADAGYGE QFSHSLGHGV
GLEIHEAPGI GATSTGTLLG ESVVTVEPGV YLPGRGGVRI EDTLVVPEEG RAQAPELLTK
FPKELAVLS
//
