ID I2B7P4_SHIBC Unreviewed; 296 AA.
AC I2B7P4; K6WEA3;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00019048};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415};
DE AltName: Full=Alpha-D-glucosyl-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00031455};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|ARBA:ARBA00031959};
DE AltName: Full=Uridine diphosphoglucose pyrophosphorylase {ECO:0000256|ARBA:ARBA00032341};
GN Name=galF {ECO:0000313|EMBL:AFJ46548.1};
GN OrderedLocusNames=EBL_c14460 {ECO:0000313|EMBL:AFJ46548.1};
OS Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 /
OS CDC 9005-74) (Escherichia blattae).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shimwellia.
OX NCBI_TaxID=630626 {ECO:0000313|EMBL:AFJ46548.1, ECO:0000313|Proteomes:UP000001955};
RN [1] {ECO:0000313|EMBL:AFJ46548.1, ECO:0000313|Proteomes:UP000001955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74
RC {ECO:0000313|Proteomes:UP000001955};
RX PubMed=22843577; DOI=10.1128/JB.00829-12;
RA Brzuszkiewicz E., Waschkowitz T., Wiezer A., Daniel R.;
RT "Complete genome sequence of the B12-producing Shimwellia blattae strain
RT DSM 4481, isolated from a cockroach.";
RL J. Bacteriol. 194:4436-4436(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890}.
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DR EMBL; CP001560; AFJ46548.1; -; Genomic_DNA.
DR RefSeq; WP_002439955.1; NZ_BAHA01000004.1.
DR AlphaFoldDB; I2B7P4; -.
DR STRING; 630626.EBL_c14460; -.
DR KEGG; ebt:EBL_c14460; -.
DR PATRIC; fig|630626.3.peg.1394; -.
DR eggNOG; COG1210; Bacteria.
DR HOGENOM; CLU_029499_1_1_6; -.
DR OrthoDB; 9803306at2; -.
DR Proteomes; UP000001955; Chromosome.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF2; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000313|EMBL:AFJ46548.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001955};
KW Transferase {ECO:0000313|EMBL:AFJ46548.1}.
FT DOMAIN 5..275
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 296 AA; 32734 MW; D31FDD5BF8C12C4A CRC64;
MTNLKAVIPV AGLGMHMLPA TKAIPKEMLP IVDKPMIQYI VDEIVAAGIK EIVLVTHSSK
NAVENHFDTS YELEALLEQR VKRQLLAEVK SICPPGVTIM NVRQGHALGL GHSILCAKPI
VGENPFVVVL PDIILDDATA DPLRYNLAAM VARFNDTGRS QVLAKRMTGD LSEYSVITTD
EKLENEGQVA RIVDFIEKPD EPQTLDSDLM AVGRYVLSAD IWAELEKVQP GAWGRYQLTD
AIAAVNQYHP VEAMLMTGQS YDCGKKLGYM QAFVQYGLRN LKEGQKFRAR VESLLD
//
