ID I2F542_9BACT Unreviewed; 504 AA.
AC I2F542;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Phospholipid/glycerol acyltransferase domain-containing protein {ECO:0000259|SMART:SM00563};
DE Flags: Precursor;
GN ORFNames=Theba_1357 {ECO:0000313|EMBL:AFK07045.1};
OS Mesotoga prima MesG1.Ag.4.2.
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae; Mesotoga.
OX NCBI_TaxID=660470 {ECO:0000313|EMBL:AFK07045.1, ECO:0000313|Proteomes:UP000002881};
RN [1] {ECO:0000313|EMBL:AFK07045.1, ECO:0000313|Proteomes:UP000002881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=mesG1.Ag.4.2 {ECO:0000313|Proteomes:UP000002881};
RX PubMed=22798451;
RA Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C.,
RA Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N.,
RA Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L.;
RT "Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima
RT MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date.";
RL Genome Biol. Evol. 4:700-708(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003532; AFK07045.1; -; Genomic_DNA.
DR RefSeq; WP_014730991.1; NC_017934.1.
DR AlphaFoldDB; I2F542; -.
DR STRING; 660470.Theba_1357; -.
DR KEGG; mpg:Theba_1357; -.
DR eggNOG; COG0204; Bacteria.
DR eggNOG; COG2020; Bacteria.
DR HOGENOM; CLU_540587_0_0_0; -.
DR Proteomes; UP000002881; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR CDD; cd07989; LPLAT_AGPAT-like; 1.
DR Gene3D; 1.20.120.1630; -; 1.
DR InterPro; IPR007318; Phopholipid_MeTrfase.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR43847; BLL3993 PROTEIN; 1.
DR PANTHER; PTHR43847:SF1; BLL3993 PROTEIN; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR Pfam; PF04191; PEMT; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002881};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 195..304
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 504 AA; 57155 MW; 7F6048AC9D597AAE CRC64;
MRIAISVAEL AVTWIIIPFL LFSGAPFSAG LGVTIVASII IILSLLLAIY SALVVYYWSG
RLPTVIYGPE KTVQSGPYRF VRHPFNLGYI LFLFGLGLLS GNYWTLLYVA VIGAVIVVYS
LLQEKLALKR IEGYEDYKEK IPFMIPNPGR KIPFDKSTSI PWQFIVASFV VKLVILIVLP
SKVKNARVLR EKRPFVLALA HQTHFDGPLI FYSTSRYLRF VGTAIYVDRL GLLNWLAVIP
VRRYAVDTSA IRQMLSTIKQ GVPLGIAPEA ARSWDGRPLH TKREIWKLFR MLKIPVIPVK
FYGVQRLWPR WAKIFALGTS TVEFGDPVEA DDPQLEEKVM GFLAKEDPTF KLPYRNYKRI
EKLIWRCPSC GAVASIKGFK TGFSCSSCGK SWTKPTVNEV IQIHDRIMPG SMGLSFPIKD
EVIFNGERVT ANIYEDHAMI GDYKLDYSVI NNSSIEKSIE PVFGIANEMV SFVSTTSALM
WQELVDFQIK FRLKKENYHT DLWG
//
