ID I2GDW8_9BACT Unreviewed; 371 AA.
AC I2GDW8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Secretion protein HlyD family protein {ECO:0000313|EMBL:CCH52092.1};
GN ORFNames=BN8_01065 {ECO:0000313|EMBL:CCH52092.1};
OS Fibrisoma limi BUZ 3.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrisoma.
OX NCBI_TaxID=1185876 {ECO:0000313|EMBL:CCH52092.1, ECO:0000313|Proteomes:UP000009309};
RN [1] {ECO:0000313|EMBL:CCH52092.1, ECO:0000313|Proteomes:UP000009309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 3T {ECO:0000313|Proteomes:UP000009309};
RX PubMed=22843583; DOI=10.1128/jb.00869-12;
RA Filippini M., Qi W., Jaenicke S., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of the Filamentous Bacterium Fibrisoma limi BUZ 3T.";
RL J. Bacteriol. 194:4445-4445(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH52092.1}.
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DR EMBL; CAIT01000004; CCH52092.1; -; Genomic_DNA.
DR RefSeq; WP_009280678.1; NZ_CAIT01000004.1.
DR AlphaFoldDB; I2GDW8; -.
DR STRING; 1185876.BN8_01065; -.
DR eggNOG; COG1566; Bacteria.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000009309; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF26; TRANSPORT PROTEIN COMB; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR PRINTS; PR01490; RTXTOXIND.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009309};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..94
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 178..312
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 166..200
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 371 AA; 39934 MW; 542B86D3A88B7954 CRC64;
MANSKKTLFR IGGVIILAVA IFFGYSEFRY LQLHETTDDA QIDGDVDPVT PKVGGYVKAI
RFNDNQYVKE GDTLVVLDDA DYRIRAAQAE AALQSALASA GVTRSSVGVA SATVQSSQAS
VQTARDNVAT AQANVAAAQA RFWKASQDFT RYERLLAERT VPQQQFDAVK AERDAAQAQL
QAAQAQLRTA QSQVNAAGTQ TSVTNSQQRV TQGQISVAQA AVKQRQAELD LARLQLSYTI
VRAPASGIVS RRAVQVGQLI QPGQALCSVV GHSNLWVTAN FKETQLQHMQ PGQRVDIDVD
AYEGEKLSGQ VGSFAGATGA RFSLLPPDNA TGNYVKVVQR IPVRIELDKN SPVYAKLRPG
MSATVAVNLQ K
//
