ID   I2GR79_9BACT            Unreviewed;       578 AA.
AC   I2GR79;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Oligoendopeptidase, M3 family {ECO:0000313|EMBL:CCH56407.1};
GN   ORFNames=BN8_05741 {ECO:0000313|EMBL:CCH56407.1};
OS   Fibrisoma limi BUZ 3.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC   Fibrisoma.
OX   NCBI_TaxID=1185876 {ECO:0000313|EMBL:CCH56407.1, ECO:0000313|Proteomes:UP000009309};
RN   [1] {ECO:0000313|EMBL:CCH56407.1, ECO:0000313|Proteomes:UP000009309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BUZ 3T {ECO:0000313|Proteomes:UP000009309};
RX   PubMed=22843583; DOI=10.1128/jb.00869-12;
RA   Filippini M., Qi W., Jaenicke S., Goesmann A., Smits T.H., Bagheri H.C.;
RT   "Genome Sequence of the Filamentous Bacterium Fibrisoma limi BUZ 3T.";
RL   J. Bacteriol. 194:4445-4445(2012).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU003435};
CC       Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC   -!- SIMILARITY: Belongs to the peptidase M3 family.
CC       {ECO:0000256|RuleBase:RU003435}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCH56407.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAIT01000009; CCH56407.1; -; Genomic_DNA.
DR   RefSeq; WP_009284972.1; NZ_CAIT01000009.1.
DR   AlphaFoldDB; I2GR79; -.
DR   STRING; 1185876.BN8_05741; -.
DR   eggNOG; COG1164; Bacteria.
DR   OrthoDB; 9762795at2; -.
DR   Proteomes; UP000009309; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd09606; M3B_PepF; 1.
DR   Gene3D; 1.10.1370.30; -; 1.
DR   InterPro; IPR045090; Pept_M3A_M3B.
DR   InterPro; IPR001567; Pept_M3A_M3B_dom.
DR   InterPro; IPR011976; Pept_M3B_oligopep-rel.
DR   NCBIfam; TIGR02289; M3_not_pepF; 1.
DR   PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR   PANTHER; PTHR11804:SF48; PUTATIVE-RELATED; 1.
DR   Pfam; PF01432; Peptidase_M3; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU003435};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU003435};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009309};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT   DOMAIN          178..557
FT                   /note="Peptidase M3A/M3B catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01432"
SQ   SEQUENCE   578 AA;  67228 MW;  9F286C016B943ED0 CRC64;
     MIQDTTLEIP TRPSRPFIGE EMELKSWEDV RPFYDNLLNR PIENADDLHQ WLLDRSELES
     YLSENFAWRY IRMTCDTSNE DLISKLNFFI ADIQPQMTAY GNDLDLKAVN SPFLSQLTDA
     GYDVMVRSMK KAIEIFREEN IPLQTEMQTE ERKYGAIAGA MTVVIDGKEV TLQQASDLLQ
     STDRAVREEA WRKIWERRYE DHESLDELFD RLRTLRHQVA VNAGFANFRD YAFAALGRFD
     YTPDDCFNFH ESVAAAVVPL LDTLANERKQ KLSVDPLRPW DSKVDPDGHP PLKPFTTSNE
     LLEKTIACFD RLDVQLGNYL RIMRAMGHLD LESRKGKAPG GYNYPLEEIG VPFIFMNATS
     SLRDLVTMVH EGGHAVHSFL TRELPLKAFR NPPMEVAELA SMSMELLSMD HWDVFFDNPE
     ELRRAKLQHL ESIIETLPWV ATIDKFQHWI YENPTHSITE REQNWLQIYD QFSDNVTDWS
     GLESFNAYVW QRQLHLYEVP FYYIEYGIAQ LGAIGIWRNY RKDPATGLQG YKDALSLGYK
     APIRAIYDAA QVPFDFSRQH IQELIGFVWE EIEQLKKS
//