ID I2JW93_DEKBR Unreviewed; 717 AA.
AC I2JW93;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Plasma membrane mg(2+) expression and turnover are regulated by mg(2+) concentration {ECO:0000313|EMBL:EIF47245.1};
GN ORFNames=AWRI1499_2828 {ECO:0000313|EMBL:EIF47245.1};
OS Brettanomyces bruxellensis AWRI1499.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Brettanomyces.
OX NCBI_TaxID=1124627 {ECO:0000313|EMBL:EIF47245.1, ECO:0000313|Proteomes:UP000004997};
RN [1] {ECO:0000313|EMBL:EIF47245.1, ECO:0000313|Proteomes:UP000004997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI1499 {ECO:0000313|EMBL:EIF47245.1,
RC ECO:0000313|Proteomes:UP000004997};
RX PubMed=22470482; DOI=10.1371/journal.pone.0033840;
RA Curtin C.D., Borneman A.R., Chambers P.J., Pretorius I.S.;
RT "De-Novo Assembly and Analysis of the Heterozygous Triploid Genome of the
RT Wine Spoilage Yeast Dekkera bruxellensis AWRI1499.";
RL PLoS ONE 7:E33840-E33840(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF47245.1}.
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DR EMBL; AHIQ01000162; EIF47245.1; -; Genomic_DNA.
DR Proteomes; UP000004997; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF55; MAGNESIUM TRANSPORTER ALR1-RELATED; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 613..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 45..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 80835 MW; 75998AACAE831039 CRC64;
MSLESNRISN NRVSFTSDRX IGXKLTSRDE EENESAVIFD DDVVXSXDGI SNHGSTRKDS
SLNRMKSNAS KSHPLHRSSS KFSRTGSKAI KRQAENLIES GRGHRTGSIL LTPANNKIRN
RTRSNSSNVN NLNPPIFKSI SRVSNNSQRK SPRKESVQSG NNDSSESESD VDSHASGDSQ
ETEEDVCFPM IPKHIRVXDV DVDELEEYIQ TEKIENEEIL KREQAIRNSS VGLNXMMTTG
SQNFSTSALK YSPKGYQLSN FSRNXLXGGG LDQNHKXDSF QIGDNVSSNS SSGNNXPASF
PQVEKFYGGE NGTSEPPNRF SFFNSKREET IHSPDISSLL APGTHVLDLF EPEDSVWWLD
CTCPTEDEMK VLAKAFGIHP LTAEDIRTQE AREKVELFKT YYFVCFHTFE DDNESEDFLE
RVNVYMVVFR QGMLTVHFSP INNPASVRRR VRQLRDYVEL SSDWLCYALV DDITDGFAPV
ISSIEYEAEA IEDTVFFLKE KDFRAMLFRI GESRRKVMTL MRLLQGKADV IKMFAKRCQE
DKKLPSVTAS QPVKPRSGIA LYLGDIQDHL ITMFQSLLSY EKVLSRAHAN YLAQLQVESF
NFNNLVTDML SKVTFLGTIL VPMNLXTGLF GMNVTVPGXD VENYGWFGGI LGFIIFVCIV
AAGLGEWYMN RLSKKASVES TSSTRSFKIG KHRNSAVYDR RTXTSLPSKF TRYGDWH
//
