ID I2K2W1_DEKBR Unreviewed; 899 AA.
AC I2K2W1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 03-MAY-2023, entry version 38.
DE SubName: Full=Putative sulfate transporter {ECO:0000313|EMBL:EIF49563.1};
GN ORFNames=AWRI1499_0440 {ECO:0000313|EMBL:EIF49563.1};
OS Brettanomyces bruxellensis AWRI1499.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Brettanomyces.
OX NCBI_TaxID=1124627 {ECO:0000313|EMBL:EIF49563.1, ECO:0000313|Proteomes:UP000004997};
RN [1] {ECO:0000313|EMBL:EIF49563.1, ECO:0000313|Proteomes:UP000004997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI1499 {ECO:0000313|EMBL:EIF49563.1,
RC ECO:0000313|Proteomes:UP000004997};
RX PubMed=22470482; DOI=10.1371/journal.pone.0033840;
RA Curtin C.D., Borneman A.R., Chambers P.J., Pretorius I.S.;
RT "De-Novo Assembly and Analysis of the Heterozygous Triploid Genome of the
RT Wine Spoilage Yeast Dekkera bruxellensis AWRI1499.";
RL PLoS ONE 7:E33840-E33840(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIF49563.1}.
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DR EMBL; AHIQ01000032; EIF49563.1; -; Genomic_DNA.
DR Proteomes; UP000004997; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR PANTHER; PTHR11814:SF263; SULFATE TRANSPORTER YPR003C-RELATED; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000004997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 256..279
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 316..338
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 433..453
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 523..546
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 558..577
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 582..600
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 620..647
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 732..872
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..733
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 99012 MW; 57A6F642E8083DCB CRC64;
MSEANLKAHS AYGSSESESS HSDAVNVIQT EENDNTQFGG PIHSSSSSSS GNSESYRSNR
YGHESRLYAN ESFPSDSTHN MDYVLGSFKK QLHTGKNPIN IQDPLIALAS PVRKSPLSHE
YNYKPNCATQ PHFHNSDITH STIXLPTPSN NLPFKALYGS IKEEGEADSI QSSTYQIASS
PLISTSSAGF IEDNLESANV AXPQSGPLSF ERKLKYYVPC CNWMAQYTLD NFFHDLVAGL
SLASYQIPLS MSFATAVAHV PTICGLLGLX VAPTIYMFLG SVPQMIVGPE AAVSMIVGQC
IEKIIKHNPD VSSVDLLIVL ASCSGSILLX FGLMRFGFID NVLCSSLMKA FITAIGVTMM
INSTISILGL DSALSSLPSD IHVHSPYQKL VFLIQHIHKF HXSTTAIGFS AFAALFIMKY
IKSLFIKRKH KWASFFPEIL VVVVFSTFMS YMLDFEKHGI NVLGKVDVSG FRLKLPFTSH
LRPWYSELFV ASFTCAILGF FESSTAAKSL SSSTTPVSSN RELVALGSVS LSVSVFGGLP
SFGGYARSKL NATNGARTPA SGLFMGLTTL LTTLYLLDYI YYLPICVLNA VIAIVGLSLL
KESPGEVKFH IRTEGYXELF TFFLTLVSSF FYTVELGVGI GTFYSLMRVI KHSTKSRIQI
LARVAGTDIF VNSDFVDDDG APLKKVAVKG YKEFRRKSMI RHRLEAGELT NNSLSEEQSV
DTDDKKDSDS DAAPQLEDRE GCLIIKIPEP LTFTNASDLK SRLKRIEIYG SAKAHPASKH
TNFRLRHIVF DLHGMTSLDS SAAQIVVDVL LNYKKRGIDV FFCRVFRDKD LLRRLKDSGI
TGTLSYFEGS NYGIPQRWPP YYDKILDALK AIDCIEYGNN SNDDVQSYIS SSFPYDGSA
//
