ID   I3C0I2_9FLAO            Unreviewed;       948 AA.
AC   I3C0I2;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Putative Zn-dependent peptidase {ECO:0000313|EMBL:EIJ37125.1};
GN   ORFNames=JoomaDRAFT_0063 {ECO:0000313|EMBL:EIJ37125.1};
OS   Galbibacter orientalis DSM 19592.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Galbibacter.
OX   NCBI_TaxID=926559 {ECO:0000313|EMBL:EIJ37125.1, ECO:0000313|Proteomes:UP000004690};
RN   [1] {ECO:0000313|EMBL:EIJ37125.1, ECO:0000313|Proteomes:UP000004690}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19592 {ECO:0000313|EMBL:EIJ37125.1,
RC   ECO:0000313|Proteomes:UP000004690};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA   Peters L., Chertkov O., Ovchinnikova G., Kyrpides N., Mavromatis K.,
RA   Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Tindall B., Brambilla E., Klenk H.-P.,
RA   Eisen J.A.;
RT   "Improved High-Quality Draft genome of Joostella marina DSM 19592.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261}.
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DR   EMBL; JH651380; EIJ37125.1; -; Genomic_DNA.
DR   AlphaFoldDB; I3C0I2; -.
DR   STRING; 926559.JoomaDRAFT_0063; -.
DR   eggNOG; COG0612; Bacteria.
DR   HOGENOM; CLU_008156_0_0_10; -.
DR   Proteomes; UP000004690; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 3.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004690};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..948
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003668661"
FT   DOMAIN          59..171
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          210..394
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          703..878
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   948 AA;  110331 MW;  542351B18C0D5271 CRC64;
     MNYLYYLLVY ILLAGANNLN AQEPENLNKE DSTLTSAVYS NQLNNGLNYY LKPIKGTTNI
     SLNLWLRAGF NEEASDQQDI SHAVEHLAFR SSVHFPEGIK NTQKLAALGI EKNDATAGTA
     YHYTRYTISI PSESQRALHN GLLWFKDILN GLLLTTEDIN IERTTLRQEF LHRAGNDLSN
     RIVKSQIDAK RNSCKKSQEF FLEDNANFPP QVVRQFYKKW YRPDLAAVSV IGDIPNLEII
     KKEIHQLFSD LPKPSTPIRK LNCDVLYYEQ EPKFYKVERP SSKPEEELSQ EVEIHLDYRD
     SLMYKEIQNV KGLKRRILFE TISAILNKRF KEQQSIYCPK FNFWMKYKEN PFFLTSQISV
     TPGYEKLALE RFFELVHQLK KYGITEKEWA TVKNDRKTQK ANHNRHWVEE IIKFDVYGEA
     LPNDKIEKLN EWWQHLSRSE FNSYLQELIR EMPEDIGIIA HKNQKAFKLK EKEVRSWIKQ
     SWISEIDPYN PPKIPEHLMD GSHLDKNISN KKLMYSSTKM GTKELTLENG VKIIFLQDSS
     IAPIKNPTIT LHGFVPYGAA NFPKEDYHSV INAPFIIENS GVGSFDKFQV NRYLSQSEDP
     INLHSYINYS ESGFTGYAKL HSFNDLLQMI YLYTTQPRKN KLAFKDWKER KRKEYSNPPY
     GLGNVDMINE IKAILKDSSF INMGTFQHQG LSNIDLNKTY TSYQNIFGNA EAFTFILYGN
     YSIEMLLPDI QKYLGNLPTN KEGILEKSTN DVPSLLNGGP LYKKLNLGYL MQSDNYQMYF
     LSRKPEVFTW KKKLQLGILG KILDQMLFLD LRYKKGYGIY SPHATTEYNI SLSRFMTSLR
     IECEPFESTA IQDDIHKIIK DIQTGKISSD HFENAKANVS SNNSSSLYRQ EQRLFEYYRY
     QIPWISKTDI DRVISETTLK DIVALAKEVF KPKNQYEFLV PSKNSVVK
//