ID I3C580_9FLAO Unreviewed; 642 AA.
AC I3C580;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:EIJ38773.1};
GN ORFNames=JoomaDRAFT_1766 {ECO:0000313|EMBL:EIJ38773.1};
OS Galbibacter orientalis DSM 19592.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Galbibacter.
OX NCBI_TaxID=926559 {ECO:0000313|EMBL:EIJ38773.1, ECO:0000313|Proteomes:UP000004690};
RN [1] {ECO:0000313|EMBL:EIJ38773.1, ECO:0000313|Proteomes:UP000004690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19592 {ECO:0000313|EMBL:EIJ38773.1,
RC ECO:0000313|Proteomes:UP000004690};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Peters L., Chertkov O., Ovchinnikova G., Kyrpides N., Mavromatis K.,
RA Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Tindall B., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Improved High-Quality Draft genome of Joostella marina DSM 19592.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; JH651379; EIJ38773.1; -; Genomic_DNA.
DR RefSeq; WP_008612054.1; NZ_JH651379.1.
DR AlphaFoldDB; I3C580; -.
DR STRING; 926559.JoomaDRAFT_1766; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_1_2_10; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000004690; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000004690}.
FT DOMAIN 46..209
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 247..577
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 642 AA; 73055 MW; 2A11D78D85E3D4B8 CRC64;
MRKLLLASII IIIAIVYIGR LSYLQLLDNT NKNPLNDTAI NAVYDYPERG HIYDRNGELL
VANQPSYDVM VIPREVKPLD TLEFCALLNI TKEEFEKKYK KARIYSPRLP SVFVPQLSKK
EYAILQEKMR KYEGFYIQKR SLRHYMTHVG ANVLGYISEV NNRDLKKYSY YQSGELIGRQ
GVEEEYENVL RGRKGVKFIQ KDRFNRVIGP YKDGVFDTLP VPGKDIVLTL DNELQKYGEK
LMIHKRGGIV ALDPKTGEIL ALVSAPSYDP DLLVGRKRSK NYTELYYDSI AKPLYDRGLN
AMYPPGSPFK TVNALIGLQE GVIDESTTFT CYHGYRYGRN SFMGCHCPSG TRNNLRRGIE
ASCNAYFANT YRRIIEKYPT SAEGMNAWEK HVESFGLGNY LGYDLPTGQS GKIPDADYYN
SVYGERRWFA TNTLSNAIGQ GEVLSTPIQL ANLTATIANR GYYYTPHIIK EIENDTIPNK
FLEKHQTTID TKNFEPVVQG MYDVYNKGTA SLLRIPGINI AGKTGTAENF TKIEGERVQL
TDHSIFVAFA PVEDPKIAIA VFVENGYWGS RWAGRIASLM IEKYVKGEIT RTDMENYLLK
GSLEEEYAKP LSGESFRIND GKTFVKWPEK EVIKQPTKKP LP
//
