ID I3IX84_ORENI Unreviewed; 385 AA.
AC I3IX84;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Cilia- and flagella-associated protein 36 {ECO:0000256|ARBA:ARBA00021815};
DE AltName: Full=Coiled-coil domain-containing protein 104 {ECO:0000256|ARBA:ARBA00031593};
GN Name=cfap36 {ECO:0000313|Ensembl:ENSONIP00000001224.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000001224.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000001224.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CFAP36 family.
CC {ECO:0000256|ARBA:ARBA00007460}.
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DR RefSeq; XP_003438492.1; XM_003438444.4.
DR AlphaFoldDB; I3IX84; -.
DR Ensembl; ENSONIT00000001223.2; ENSONIP00000001224.1; ENSONIG00000000967.2.
DR GeneID; 100696680; -.
DR KEGG; onl:100696680; -.
DR CTD; 112942; -.
DR eggNOG; KOG4511; Eukaryota.
DR GeneTree; ENSGT00390000012785; -.
DR HOGENOM; CLU_050059_0_0_1; -.
DR OrthoDB; 180864at2759; -.
DR TreeFam; TF315143; -.
DR Proteomes; UP000005207; Linkage group LG13.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1520.10; ADP-ribosylation factor-like 2-binding protein, domain; 1.
DR InterPro; IPR023379; BART_dom.
DR InterPro; IPR042541; BART_sf.
DR InterPro; IPR038888; CFAP36.
DR PANTHER; PTHR21532:SF0; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36; 1.
DR PANTHER; PTHR21532; PHOSPHODIESTERASE HL; 1.
DR Pfam; PF11527; ARL2_Bind_BART; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 6..118
FT /note="BART"
FT /evidence="ECO:0000259|Pfam:PF11527"
FT REGION 203..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 144..178
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 203..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..339
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 385 AA; 42937 MW; 49DE9447AEE2CA82 CRC64;
MAEDDSEWVL ESIVGYLGSP EWVVPVTDFL ENKCTVFDDE DENKLAYTEI HEQYKKLVEK
LLENYMQEVG INEQQFLDAC TSPFAKSKAL EAVFQPVLAT DDFQMFRSLM VHKNMELQLQ
ALRVIKERNG ALPECLTDGV DVMTELQQQE MKILQEVLKK SKEEYDEEMS RRLLLEKEVG
STSSGCSSKL MAECDEAKNT ASALSQHISP AKVNSNPVRK EGSKTAATGG GAERSSSSKP
TSDRGSDAVG ARVLPAVRGP VKSAEPSISS SRHAGEQSNS SQTTSEAWLE EAHREAGFSK
PYTELSTSQQ EQLQQRAAYL RQQRDKLHAL RKEQQKTKQS SLPEEAPSSP TPAPSTTPEI
SAEEKKKLEK RKHLADKLKE EVIKK
//
