ID I3IZI4_ORENI Unreviewed; 483 AA.
AC I3IZI4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Noelin-2 {ECO:0000313|Ensembl:ENSONIP00000002024.1};
GN Name=LOC100706999 {ECO:0000313|Ensembl:ENSONIP00000002024.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000002024.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000002024.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
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DR RefSeq; XP_003442137.1; XM_003442089.4.
DR AlphaFoldDB; I3IZI4; -.
DR Ensembl; ENSONIT00000002023.2; ENSONIP00000002024.1; ENSONIG00000001613.2.
DR GeneID; 100706999; -.
DR KEGG; onl:100706999; -.
DR CTD; 334035; -.
DR eggNOG; KOG3545; Eukaryota.
DR GeneTree; ENSGT00940000159148; -.
DR HOGENOM; CLU_035236_0_0_1; -.
DR InParanoid; I3IZI4; -.
DR OMA; HQVVYNV; -.
DR OrthoDB; 2876896at2759; -.
DR TreeFam; TF315964; -.
DR Proteomes; UP000005207; Linkage group LG4.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR InterPro; IPR022082; Noelin_dom.
DR InterPro; IPR003112; Olfac-like_dom.
DR PANTHER; PTHR23192:SF27; NOELIN-2; 1.
DR PANTHER; PTHR23192; OLFACTOMEDIN-RELATED; 1.
DR Pfam; PF12308; Noelin-1; 1.
DR Pfam; PF02191; OLF; 1.
DR SMART; SM00284; OLF; 1.
DR PROSITE; PS51132; OLF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00446}; Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 224..476
FT /note="Olfactomedin-like"
FT /evidence="ECO:0000259|PROSITE:PS51132"
FT DISULFID 225..407
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00446"
SQ SEQUENCE 483 AA; 54984 MW; C3EECA6AF5338EF3 CRC64;
MSVPMLKIGA VLSTMAMVTN WMSQTLPSLV GLNGTTISRG GTSERIVSAL YPRPEEGWEI
YSSAQDADGK CICTVVAPAQ NMCNRDPRSR QLRQLMEKVQ NISQSMEVLD LRTYRDLQYV
RNTESLMKVV DGKLKVASEN PRSLNPKGFQ ELKDKVTQLL PLLPVLEQYK TDAKMILRLR
EEVRNLSLVL MAIQEEMGAY DYEELRQRVL LLETRLHSCM QKLGCGKLTG VSNPITVRAS
GSRFGSWMTD TMIPSSDNRV WSMDGYFKGR RVLEYRTMND FMKGQNFVQH LLPHPWAGTG
HVVYNGSLYY NKYQSNIIIK YHFRSRSVLV QRSLSGAGYN NTFPYSWGGS SDIDLMADEN
GLWAVYTTIP NAGNIVISRL EPQSLEVLQT WDTGFPKRSA GESFMICGTL YVTNSHLAGA
KIYFAYYTNT SSYEYTDIPF HNQYSHISMM DYNPRERVLY TWNNGHQVLY NVTLFQVIKT
SGD
//
