ID   I3IZZ0_ORENI            Unreviewed;       692 AA.
AC   I3IZZ0;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Zgc:153738 {ECO:0000313|Ensembl:ENSONIP00000002180.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000002180.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000002180.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; I3IZZ0; -.
DR   Ensembl; ENSONIT00000002180.2; ENSONIP00000002180.2; ENSONIG00000001741.2.
DR   eggNOG; KOG0740; Eukaryota.
DR   GeneTree; ENSGT00940000154067; -.
DR   InParanoid; I3IZZ0; -.
DR   OMA; VCHETGA; -.
DR   TreeFam; TF324350; -.
DR   Proteomes; UP000005207; Linkage group LG23.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR14690:SF6; IQ AND AAA DOMAIN-CONTAINING PROTEIN 1-LIKE; 1.
DR   PANTHER; PTHR14690; UNCHARACTERIZED; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF00612; IQ; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00015; IQ; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN          432..571
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          665..692
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        669..685
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   692 AA;  78929 MW;  CBB0ABEBF991F5E4 CRC64;
     RTEDAQLELS CLLAEELPAE PPRPEKDRVV FFQRLAMLFV RYTQIFRQLE KAYDLVVHPQ
     KRRFIRSVLD SVMGRVLELK NEMVEKEFSE YHYMDDVLHD LKLIPADLEI PIPRYFHSER
     SKEVQQRKAM LTDILKMVEV TETPEVSGKA AKSFKALKLS RLILKIIQVA ERARQGRERA
     KFNMKNLNMN TVYRIKEPGA DSAESAAVCI QKVWKGYVQR KRTKTAREEE MIFLGMTMDP
     KYEAPRPAEM TAQAIEASTR VKQMEHEEAY QKATVDVMNQ LRDVEGDDMS KSMKVQIQQW
     FTECRNATGT FPDYPDEEDG GSALIFAEKT PQQVDEQMRQ ELAEWKLSVD KDKGGKTKSG
     KKKKKEKDLT ADRTFVLCKT AVYSLGDYSY LGTTLRQHDI EPMPSLSDVR QVISLYAVLP
     LGSQVVHEKA PLIKSVLLVG PTGVGKKMLV HAVCHETGAC LFDLSPLNTA GKYPGKSGLA
     MMLHLVFKVA RLMQPSVIWI EDAEKMFYKK IPKEEKELDP KRLKKDLPKF LKLIKGEDRV
     LIIGTTRDPH SAEIKSLCKM FSKILLIPRP DYGSRRILWK QLIRKHGGEV TEALDLSSLA
     KISDGYTPGH IVQVIQSVLT KHRIFQQAKR PLTAAEFIAP LAQIDPVFQE EEEALKSWYA
     KTPLGKKRTK AASGKEEEEP PKGKNAKKKG KK
//