ID I3JJ99_ORENI Unreviewed; 1916 AA.
AC I3JJ99;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSONIP00000008943.2};
GN Name=LOC100702482 {ECO:0000313|Ensembl:ENSONIP00000008943.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000008943.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000008943.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSONIT00000008948.2; ENSONIP00000008943.2; ENSONIG00000007087.2.
DR eggNOG; KOG2127; Eukaryota.
DR GeneTree; ENSGT00940000155836; -.
DR TreeFam; TF313237; -.
DR Proteomes; UP000005207; Linkage group LG1.
DR GO; GO:0000813; C:ESCRT I complex; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.100.10.50; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR023341; MABP.
DR InterPro; IPR018798; MVB12A/B.
DR InterPro; IPR002885; Pentatricopeptide_rpt.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR NCBIfam; TIGR00756; PPR; 1.
DR PANTHER; PTHR12296:SF16; C-MYC PROMOTER-BINDING PROTEIN; 1.
DR PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF10240; DUF2464; 1.
DR Pfam; PF13812; PPR_3; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS51498; MABP; 1.
DR PROSITE; PS51375; PPR; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 42..199
FT /note="MABP"
FT /evidence="ECO:0000259|PROSITE:PS51498"
FT DOMAIN 191..655
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REPEAT 822..856
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REGION 291..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 908..1008
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1099..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1163..1233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1256..1275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1318..1395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1461..1525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..935
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..997
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1100..1119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1167..1217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1335..1366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1916 AA; 211569 MW; D55FB0F3003BC874 CRC64;
MMEDKGPRVA DYFVVAGLTD PSKPLDQEIH FDDVCHKTAK PKAPITDVAV VIRSAGEEVP
PGFTCIETTP TGQSADLNNG ALMAPQILLC YRRGCDKPPL TDLGVLYEWK ERLKQGCHLI
QTTPSGRPAN ISGNSSQRIY ITYRRAPESQ PHAALAVTDV CIIIPSKGET PPHTFCKVEK
NLNSSMWGSS VYLCYKKSVA KTNTIAYKAG LFSRYPEEDY ESFPLPESVP LFCLPMGATI
ECWPANTKYS LPVFSTFVLT GASGEKVYGA AIQFYEPYPQ ECLTDQQVSQ LGLQNPDPHK
PSPSSSMAAG TSSTANGSPC SVYTNKCICL LSHWPFFDAF RKFLTFLYRY SISGPHALPI
EKHISHFMHK VPFPSSQRPR ILVQLSPHDS LMLSQPVSSP LPLSGGRFST LLHNLGPENA
VTLLVFAVTE HKILIHSLRP AVLTSVTEAL VSMIFPFHWP CPYIPLCPLA LADVLSAPCP
FIVGVDSRYF DLYDPPPDVS CVDLDTNTIF HHEDKRALTW KILPKKACKN LMNVLNNLYQ
QLVDGQYRPD GLLELSMSDS SELSCGKSLH TLELEIQEAF LRFMAAILKG YRSFLRPITQ
APSEKATDAS SLFDLQGFLK SRDRSHQKFY SLMTKTQMFI RFIEECSFVS DKDASLAFFD
DCVDKVDSDR PEETRLIEID ESQRSEHTVF ITPPELPPLP EGEEHPLCYR YDGFPVLSLD
LFDPVEGLRT PSSRLAARHS CPTSPAPMFR RTKQEIKSAQ KIAKKYSSIP QLWSKCLLRH
CYGLWFICLP AYVKVCHSKV RALRTAYDVL RKMQAKKLQP PDEVCYRVLM QLCGQYGQPV
LAVRVLFEMK KAGVHPNAIT YGYYNKAVLE STWPSSTRGG YFLWMKLRNV ILGVAQFKRA
LRRHAGLTQS PLSDGSDLDA VSHGSLDSSA DTNLVEQGPY AADSVKVDPT DDRSSTGDQS
DLGYNSLSKE EVRRGEPAGQ DSAPDKDDKK ESDCSSLSET ESAKGSKDCL PQLDLEMSSS
FRPRGIVRSS CPFDDSACKP KSSASADHVA GLLFTTSLDE IGEIQTNSLL RRHKSALEEV
MGSASSGSAL DWQGVKSRRL SGDTVGSSGS GTTVLGLGMS QGETDPDKIA GHLGADAKIL
AGANFTKTRR PHSLALGGLE GVAAKSHAAR SSDHREVDEE AERQDSSDED RNTTEAIFDL
EDLDFEKPSK GAKPYKKPVE RSASYGGVST MTNRGTVKRT GIETGYDPLS LLAAESDQQN
EERYTEGDQA STPSARRHLA REIELYMNHM GSPLSSHMPS LDLQDPASPV LLHHSSLSAS
SRRASLPHSS PLRTAGVPRS RTFQPPSPSQ PISRQRLWSS PPSRSSSTTP SPSPRPSPYR
ERADRMSLTS PSLSSSSFAL DTLLTPTLDV FKTSVFSAGK EVAEKASRWY TRLATYTTPT
KDSQSDHLSV SSLCAGDPDC SSLLDDEDSG DTEHSMVFPL RNGPVGPPGP RRSPRRSPLR
SHLDSPTAGS SHRRPTSLLP GLPGFSLPDK SDLSSSRYTS NTSIFNNYAM ELLISSCSRC
KTCDCLVYDE EIMAGWTADD SNLNTTCPFC GNPFLPFLNV EIRDMRGPGR LFLKGSPSVD
EAMTSSYSAS TGLDTGTSTL STPCPTTAVS PPSPMIAMQE CSARSRSTRD QGINIPVEHR
QGALSSGAPI VRSVSAFGPL DETTRQNCCL PTSGSLPSCL NEATDPLSME WRLHNPEPVT
VPYLSPLVLW KELESLLENE GDSVITEADM VDHHPIIYWN LVWYFRRLDL PSNLPGLILT
SEHCNRDSQI PRHWMSEDSK HVLIQILWDN LKLHQDPIQP LYILWNTYRL NCTLLLERAV
FSFIHAAQRR HKYETREQNR GDVHVCSQGS AMLVTLCLGQ SQRKKSRSVR SCCTVW
//
