ID I3JNT1_ORENI Unreviewed; 530 AA.
AC I3JNT1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=TRIO and F-actin binding protein {ECO:0000313|Ensembl:ENSONIP00000010525.2};
GN Name=triobp {ECO:0000313|Ensembl:ENSONIP00000010525.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000010525.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000010525.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3JNT1; -.
DR STRING; 8128.ENSONIP00000036023; -.
DR Ensembl; ENSONIT00000010534.2; ENSONIP00000010525.2; ENSONIG00000008372.2.
DR eggNOG; KOG4807; Eukaryota.
DR GeneTree; ENSGT00940000157340; -.
DR HOGENOM; CLU_011327_1_0_1; -.
DR TreeFam; TF329258; -.
DR Proteomes; UP000005207; Linkage group LG4.
DR CDD; cd13275; PH_M-RIP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR039597; M-RIP_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR17271; PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR17271:SF10; TRIO AND F-ACTIN-BINDING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 15..111
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 114..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 250..277
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 304..368
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 397..497
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 123..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 60461 MW; 393DE8C010263291 CRC64;
MTGQTREIIL SPDLLNFKKG WMSKLDERGE WKKHWFVLTD AGLKYYRDST AEEKDDLDGE
IDLKSCVNVS EFDVEKNYGF QIQTREAVFI LSAMTAGIRR NWIEVLKKCI RPSSSPDITQ
LPDSDKENSH DRVLLPSRRP TSRHGEAQSE IPASTPSSHR RFDYVELSPV PASSSLRLAS
QREAGEGQGR EHSQRQEERN TSSQWDAVLS RKGTGSNQKL RMEEEIEKKW AEFEQMPVKE
MSSLPSVGSR ASGQTANEAL QREVASLRQQ VEQLQRKGGE GGGGGVRGGC GPEAPCSRSL
LAMERAHRQA LEELQKQHDR QVKELEAQKD RLLLQEAQDT ARVMEALKKK HKEELEREVE
KVKRLSSGAV DSQTLRALHQ AEAQASQREL TGLSERYSQK CLELNRAEQN NAEREREISR
KERDMEQLRK ENQDLKARLT EEMKRIQSAI RDHGSEDNKN RMPCELEVLL RMKDNEIQYL
QKEISCLRNE LQFLNMVLCV CVCVSDSSAS LANYSLSSSD IENRDFSPSQ
//
