ID I3K3T5_ORENI Unreviewed; 529 AA.
AC I3K3T5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Polypyrimidine tract binding protein 3 {ECO:0000313|Ensembl:ENSONIP00000015780.2};
GN Name=PTBP3 {ECO:0000313|Ensembl:ENSONIP00000015780.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000015780.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000015780.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3K3T5; -.
DR Ensembl; ENSONIT00000015795.2; ENSONIP00000015780.2; ENSONIG00000012535.2.
DR GeneTree; ENSGT01050000244924; -.
DR Proteomes; UP000005207; Linkage group LG7.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR CDD; cd12693; RRM2_PTBP1_like; 1.
DR CDD; cd12425; RRM4_PTBP1_like; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592:SF27; HEPHAESTUS, ISOFORM Y; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR Pfam; PF13893; RRM_5; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 56..130
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 177..253
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 333..407
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 452..527
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 529 AA; 58062 MW; 468281C135D81CA0 CRC64;
MVKMLAVKTN RSSELKLNSS YLNPSHHNLP VCFGLSAVDG TDRLCVSERA QCIPSRVLHL
RQLPPDVSEQ EVLSLALPFG RVSKLITLKT KNQAFLEMAS EEAAVTMVNY YTSATPSIRS
QPVYIQYSTH RELKTDNMTS QRAQAALQAI NAGAVHSGNM TSGGEGRGIA PGQSPVLRII
VENLFYPVTL EVLQQIFSKF GSVLKIITFT RNNQFQALLQ FSDTVHAQHA KATLDGQNIY
NGCCTLRIDF SKLSALNVKY NNDKSRDFTR ADLPSGELEP TAAFGKATRV ALPPYGAAFW
HSPSSGLSMA AVPGSLVSHP RVSLQMAPPV VHSVLLVSNL NPESVTPHCL FILFGVYGDV
QRVKILFNKK ENALVQMSDA TQAQLAMSHL NGQRLHGNVI RVTLSKHPVV QLPRGGAGQE
EQALTRDFSG SALHRFKKPG SKNFNNIFPP SATLHLSNIP SSVSEEALKD LFSSNGFAVK
AFKFFQKDRK MALMQLASVE EAIEALIILH DHQLDHNQHL RVSFSKSTI
//
