ID I3K7I5_ORENI Unreviewed; 639 AA.
AC I3K7I5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Myosin XVB {ECO:0008006|Google:ProtNLM};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000017080.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Ensembl:ENSONIP00000017080.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314}.
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DR AlphaFoldDB; I3K7I5; -.
DR STRING; 8128.ENSONIP00000017080; -.
DR Ensembl; ENSONIT00000017095.2; ENSONIP00000017080.2; ENSONIG00000013582.2.
DR eggNOG; KOG4229; Eukaryota.
DR GeneTree; ENSGT00930000151032; -.
DR HOGENOM; CLU_021039_0_0_1; -.
DR InParanoid; I3K7I5; -.
DR OMA; FLRRVMW; -.
DR Proteomes; UP000005207; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd12068; SH3_MYO15B; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR035489; MYO15B_SH3.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR22692; MYOSIN VII, XV; 1.
DR PANTHER; PTHR22692:SF16; MYOSIN XVB; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 127..188
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 197..360
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 366..639
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
SQ SEQUENCE 639 AA; 72383 MW; FB2B4700E69CF233 CRC64;
MKDLLANFNI GTTINTIQDN NMKKRIVIAA RDNWENYFTR LFPVKVRRVL GVSHRGIRLL
KMVRALGINP KHLRLLKGYS FAEVLSADLQ GEDTVALELK SEKLVLQSRR APQIIAMIQL
FIQELIKDSN HVVALKSFVT DDKSLLSFNK GDIIKLLPME GLEPGWRFGN KGGRSGLFPE
NLTQPSAAPD YHCFNLNHRD EKRKSMRKTR SVIFNLELTV MCVFFTQTPI QESLILYNDP
EIKELSIQCF TKCLRQILLL GKEKELLRDE IFCQVIKQTT NNPKKSSCSL GWQLLSVVAG
FFPCSTTLQP YITRYLDDIS QDYEHPYHEL ASLSHDNLQR SLRFGGRRNI PSYPEIEAIL
AGQTSIYIPI HLPGGVEFPI QIKNFSVTED VVMELCKEMG INQLNEIKEF SILVIRQQDG
MVRPLHFEEY LFDFLVEDNS SSLFLRRVMW RIPLSFINDL YVDFHYQQLL ADYLNGQLML
PPVTGGSSTI QQIAMLSALQ HLALGLQDQP SLSEIKGYLP PQTGLRNKVE EILTFCQGRI
AAMQSLSPQH AKVQFIGSSL PLFGSNTFQA EKVSQRGCPS PCVVCINQEG LLFLHSKTQV
SCAPFTPNKK GKVPAVDIDY GNPAAPKKIT IHLKQVITS
//
