ID   I3KGS7_ORENI            Unreviewed;      1040 AA.
AC   I3KGS7;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 2.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Zinc finger MIZ domain-containing protein 1 {ECO:0000313|Ensembl:ENSONIP00000020322.2};
GN   Name=ZMIZ1 {ECO:0000313|Ensembl:ENSONIP00000020322.2};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000020322.2, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000020322.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; I3KGS7; -.
DR   STRING; 8128.ENSONIP00000030474; -.
DR   Ensembl; ENSONIT00000020339.2; ENSONIP00000020322.2; ENSONIG00000016133.2.
DR   eggNOG; KOG2169; Eukaryota.
DR   GeneTree; ENSGT01030000234539; -.
DR   TreeFam; TF316952; -.
DR   Proteomes; UP000005207; Unplaced.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR040797; Zmiz1_N.
DR   InterPro; IPR004181; Znf_MIZ.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10782:SF7; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF18028; Zmiz1_N; 1.
DR   PROSITE; PS51044; ZF_SP_RING; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00452}.
FT   DOMAIN          725..812
FT                   /note="SP-RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51044"
FT   REGION          115..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          179..280
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          391..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          494..522
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          848..1040
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..236
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        417..437
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..522
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        858..883
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        909..967
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        974..996
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1023..1040
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1040 AA;  112500 MW;  5706D32862C72F24 CRC64;
     MNSIPSMDRH IQQTNDRLQC IKQHLQNPAN FQTAATELLD WCGDPRAFQR PFEQSLMGCL
     TVVSRVAAQQ GFDLDLGYRL LAVCAANRDK FTPKSAALLS SWCEELGRLL LLRHQKNRQN
     EPPGKVPMQP PMSSMKPSLS HGDGSFPYDS VPWQQNTNQP PGSVSVVTTV WGVTNTSQSQ
     VLGNPMANSN NPMNPGGNPM ASGMSGNTPG MNSPQFPGPQ QQFPNKGNSN PAYMQQGMYG
     RPNYPGGGGF GGNYPGGPNA GPGGMGIPPH SRPPSDFTQP AAAAAAAAVA AAAATATATA
     TATVAALQET QNKDMNQYGP MSSSFQMGPN QAYNSQFMNQ PGPRGPPSLP GNMGTGMNAA
     NMSGPPMGMN QPRGQGMGPF GAHGQRMPQQ GYAGPRAQGM GMQGIKRPYP GEPNYGGQQY
     GPNNQFPNQQ GQYPTPNASR PLPSPNYPGP RMPGQQLQGQ YPPPSGAMGQ YYKPPFNGQT
     NNFSGSGYQY NQGNMNGPPR PVGNYPHSPV PGNPTPPMTP GSNIPPYLSP NQDVKPPFPP
     DIKPNITALP PPPASHNEEL RLTFPVRDGV VLEPFRLEHN LAVSNHVFHL RPSVHQTLMW
     RSDLELQFKC YHHEDRQMNT NWPASVQVSV NATPLTIERG DNKTSHKPLH LKHVCQPGRN
     TIQITVTACC CSHLFVLQLV HRPSVRSVLQ GLLKKRLLPA EHCITKVKRN FSSVAASSGN
     TTLNGEDGVE QTAIKVSLKC PITFRRIQLP ARGHDCKHVQ KYTLKNQFSC SCRVHALVDQ
     YMWGILNAIQ NSEFEEVTID PTCSWRPVAI KSEIHIKEDP DGPLAKRFKT MSPSQMIMPN
     VMEMIAQLGP GPSPYPSLPS GQGGNNSEYG SQGSNSYQSH GNFDFPHGTP GGTSMNDFMH
     GPQLSHPPDM PNNLMTQDKP LSHNMPDTIP HSVGNDQPHG PLQQSLHASP HPGSQSGQQL
     HHSGPPQPSR QQPGPNNHPH SDLAFNPSSG LDSQAGSDMP EPSLDLLPEL ANPDELLSYL
     DPPDLPSNSN DDLLSLFENN
//