ID I3KUZ6_ORENI Unreviewed; 465 AA.
AC I3KUZ6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSONIP00000024942.2};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000024942.2, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Ensembl:ENSONIP00000024942.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; I3KUZ6; -.
DR Ensembl; ENSONIT00000024963.2; ENSONIP00000024942.2; ENSONIG00000019814.2.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT01040000240400; -.
DR HOGENOM; CLU_013137_0_1_1; -.
DR InParanoid; I3KUZ6; -.
DR OMA; NENEYAA; -.
DR TreeFam; TF351086; -.
DR Proteomes; UP000005207; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF586; E3 UBIQUITIN-PROTEIN LIGASE TRIM39-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 17..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 86..126
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 260..454
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 158..207
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 465 AA; 52924 MW; 65ED07DD9273EE76 CRC64;
PAWAPFAPGP SLDQFLCSIC LDVFTDPVST PCGHNFCKTC ISQHWDLNQR CQCPMCKETF
NIRPQLRVNT FISEMVAQFR REAQQKASRM CTKHDKHLEL FCKTDQTCVC TLCPILDHKN
HEFVPLREEY EGKKSVKMSK DAADRQKAEG VQVFTALMES VERCLKKFIK EIEDKQETTE
KQAEGLIKDL EQEISELMKR SSEVEQLSRS EDHLHLLQSF SSLKTVPPTK DWTEVRVRLP
SYEGTVVRAV DQLEETLWKP MKKKLFEAEL KRVQQYAVDV TLDPDTAYPS LILSNDGKQV
YDSDVKKKLP DNPERFSRGA CVLGKQSFSS GRFYFEVQVK GNTEWDLGVA RESINRKGSI
TLRPQNGVWA MWLRNENEYA ALAGPRVPLC LQPGPEKVGV FVDYEEGLVS FYDVGAAALI
YSFTGCSFTH KLHPFFGPFA YTTLTQPNYL DPLTSLTEPL DLGSA
//
