ID I3LXD6_ICTTR Unreviewed; 516 AA.
AC I3LXD6;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Keratin 82 {ECO:0000313|Ensembl:ENSSTOP00000000724.2};
GN Name=KRT82 {ECO:0000313|Ensembl:ENSSTOP00000000724.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000000724.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000000724.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; AGTP01037423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005325044.1; XM_005324987.1.
DR AlphaFoldDB; I3LXD6; -.
DR STRING; 43179.ENSSTOP00000000724; -.
DR Ensembl; ENSSTOT00000000810.3; ENSSTOP00000000724.2; ENSSTOG00000000814.3.
DR GeneID; 101968328; -.
DR CTD; 3888; -.
DR eggNOG; ENOG502QWIE; Eukaryota.
DR GeneTree; ENSGT00940000161849; -.
DR HOGENOM; CLU_012560_6_1_1; -.
DR InParanoid; I3LXD6; -.
DR OMA; LPRMVTH; -.
DR OrthoDB; 4640531at2759; -.
DR TreeFam; TF317854; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0045095; C:keratin filament; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF12; KERATIN, TYPE II CUTICULAR HB2; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 118..429
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 227..254
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 327..404
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 516 AA; 57108 MW; CDB26872C48A1CC9 CRC64;
MSCRSFQAGS RYGTQNFSSC SAIMPRVVTH YEVSKGPCRT GAGGGLRALG CLGSRSLCNV
GFGRPRVASR CSLPGFGYRA GATCGSSACI TPVTINESLL VPLELEFDPT VQRVKRDEKE
QIKCLNNRFA SFINKVRFLE QKNKLLETKW NFMQQQRCCQ SNLEPLFEGY ICALRRQLDC
VSGDHTRLES ELCSLQEALE GYKKKYEEEL SLRPCAENEF VALKKDVDTA FLVKADLETN
VEALEQEINF MKGLFEEEIL LLQSQISETS VIVKMDNSRD LDVDGIVAEI KAQYDDIASR
SKAEAEAWYQ CRYEELRQTA GNHCDNLRNR KNEILEMNKL IQRLQQDIET VKAQRCKLEG
AVAEAEQQGE AALSDAKCKL SGLEEALQKA KQDMARQLKE YQEVMNFKLG LDIEIATYRR
LLEGEEHRLC EGIGPVNISV SSSKGAVLYE PCVVGTPVLR TEYCPGSTGV LRSSGGCSVV
GTGELYIPCE AQGLLGCGSG RSSNMKLATG GSSCTH
//
