ID I3MAC5_ICTTR Unreviewed; 546 AA.
AC I3MAC5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Myelin expression factor 2 {ECO:0000313|Ensembl:ENSSTOP00000006938.3};
GN Name=MYEF2 {ECO:0000313|Ensembl:ENSSTOP00000006938.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000006938.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000006938.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01002555; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3MAC5; -.
DR SMR; I3MAC5; -.
DR STRING; 43179.ENSSTOP00000006938; -.
DR Ensembl; ENSSTOT00000007751.3; ENSSTOP00000006938.3; ENSSTOG00000007740.3.
DR eggNOG; ENOG502QV3I; Eukaryota.
DR GeneTree; ENSGT00940000157397; -.
DR InParanoid; I3MAC5; -.
DR TreeFam; TF313406; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12658; RRM1_MYEF2; 1.
DR CDD; cd12660; RRM2_MYEF2; 1.
DR CDD; cd12662; RRM3_MYEF2; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR034630; MYEF2_RRM1.
DR InterPro; IPR034631; MYEF2_RRM3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23003:SF15; MYELIN EXPRESSION FACTOR 2; 1.
DR PANTHER; PTHR23003; RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 46..124
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 179..256
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 469..545
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 546 AA; 58612 MW; 237825962FA2C81A CRC64;
ENDESVKEEK SDLKEKSSGN KKANRFHPYS KDKNLGTGEK KGPNRNRVFI SNIPYDMKWQ
AIKDLMREKV GEVTYVELFK DAEGKSRGCG VVEFKDEEFV KKALETMNKY DLSGRPLNIK
EDPDGENARR ALQRTGGSFP GGHVPDMGSG LMNLPPSILN NPNIPPEVIS NLQAGRLGST
IFVANLDFKV GWKKLKEVFS IAGTVKRADI KEDKDGKSRG MGTVTFEQAI EAVQAISMFN
GQFLFDRPMH VKMDDKSVPH EDYRSHDSKT PQLPRGLGGI GMGLGPGGQP ISASQLNIGG
VMGNLGPSGM GMDGPGFGGM NRIGGGIGFG GLEAMNSMGG FGGVGRMGEL YRGAMTSSME
RDFGRGDIGI NRGFGDSFGR LGSAMIGGFA GRIGASNMGP VGSGISGGMG GMNSVTGGMG
MGLDRMSSSF DRMGPGIGAI LERSIDMDRG FLSGPMGSGM RDRIGSKGNQ IFVRNLPFDL
TWQKLKEKFS QCGHVMFAEI KMENGKSKGC GTVRFDSPES AEKACRIMNG IKISGREIDV
RLDRNA
//
