ID I3MAJ4_ICTTR Unreviewed; 491 AA.
AC I3MAJ4;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=SVOP like {ECO:0000313|Ensembl:ENSSTOP00000007021.3};
GN Name=SVOPL {ECO:0000313|Ensembl:ENSSTOP00000007021.3};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000007021.3, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000007021.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR EMBL; AGTP01069990; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01069991; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3MAJ4; -.
DR STRING; 43179.ENSSTOP00000007021; -.
DR Ensembl; ENSSTOT00000007846.3; ENSSTOP00000007021.3; ENSSTOG00000007843.3.
DR eggNOG; KOG0253; Eukaryota.
DR GeneTree; ENSGT00940000158632; -.
DR HOGENOM; CLU_001265_46_0_1; -.
DR InParanoid; I3MAJ4; -.
DR TreeFam; TF313465; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17442; MFS_SVOPL; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23511:SF44; SVOP LIKE; 1.
DR PANTHER; PTHR23511; SYNAPTIC VESICLE GLYCOPROTEIN 2; 1.
DR Pfam; PF00083; Sugar_tr; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..486
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 491 AA; 54092 MW; DCB2F3DDA02116C6 CRC64;
MAAKQTEPVT VISLRKLSLG VPEPQQQKEL KTFTVEDAVE TIGFGRFHVA LFLIMGSTGV
VEAMEIMLIA VVSPVIRCEW QLENWQVAFV TTMVFFGYMV SSILFGLLAD RYGRWKILLI
SFLWGAYFSL LTSFSPSYIW FVFLRTMVGC GVSGHAQGLI IKTEFLPTKY RGYMLPLSQV
FWLAGSLLII GLASVVIPTI GWRWLIRIAS IPGIILIMAF KFIPESARFN VSTGNTQAAL
ATLERIARMN RSVMPEGRLV EPILEKRGRF ADLLDAKYLR TTLQIWVIWL GISFAYYGVI
LASAELLERD LVCGSKSESQ VVVVTGGDSQ ESHSPCHCHL FAPSDYRTMI ISTIGEIALN
PLNILGINFL GRRLSLAITM GCTALFFLLL NICTSSAGLI GFLFMLRALV AANFNTIYIY
TAEVYPTTMR ALGMGTSGSL CRIGAMVAPF ISQVLMSASF LGALCLFSSV CVVCAISAFT
LPIETKGRAL Q
//
