ID I3MRW1_ICTTR Unreviewed; 272 AA.
AC I3MRW1;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=TGFB induced factor homeobox 1 {ECO:0000313|Ensembl:ENSSTOP00000014856.1};
GN Name=TGIF1 {ECO:0000313|Ensembl:ENSSTOP00000014856.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000014856.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000014856.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
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DR EMBL; AGTP01091399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005337168.1; XM_005337111.1.
DR RefSeq; XP_005337169.1; XM_005337112.1.
DR RefSeq; XP_013219137.1; XM_013363683.1.
DR STRING; 43179.ENSSTOP00000014856; -.
DR Ensembl; ENSSTOT00000022454.2; ENSSTOP00000014856.1; ENSSTOG00000027485.2.
DR Ensembl; ENSSTOT00000033014.1; ENSSTOP00000024581.1; ENSSTOG00000027485.2.
DR GeneID; 101965583; -.
DR CTD; 7050; -.
DR eggNOG; KOG0773; Eukaryota.
DR GeneTree; ENSGT00940000155230; -.
DR HOGENOM; CLU_034318_2_0_1; -.
DR OMA; FPLCQSV; -.
DR OrthoDB; 3180467at2759; -.
DR TreeFam; TF318093; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR PANTHER; PTHR11850:SF59; HOMEOBOX PROTEIN TGIF1; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 33..96
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 35..97
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 272 AA; 29661 MW; DCFF494F9135C72A CRC64;
MKSKKGVVAA SGSETEDEDS MDIPLDLSSS AGSSKRRRRG NLPKESVQIL RDWLYEHRYN
AYPSEQEKAL LSQQTHLSTL QVCNWFINAR RRLLPDMLRK DGKDPNQFTI SRRGAKVSEA
SSMEAAIGIK NFMPPLEESP FHSCTAGPNP TLGRPLSPKP ASPGSILARP SVICHTTVTA
LKDVPFPLCQ SVGVGQTTDI QQMAASNFTD TSLVYPEDTC KSGPSTNTQS GLFNTPPPTP
PDLNQDFSGF QLLVDVALKR AAEMELQAKL TA
//
