ID I3MTH8_ICTTR Unreviewed; 256 AA.
AC I3MTH8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Regulatory factor X associated ankyrin containing protein {ECO:0000313|Ensembl:ENSSTOP00000015423.2};
GN Name=RFXANK {ECO:0000313|Ensembl:ENSSTOP00000015423.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000015423.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000015423.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01071244; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005333016.1; XM_005332959.2.
DR RefSeq; XP_013217321.1; XM_013361867.1.
DR AlphaFoldDB; I3MTH8; -.
DR STRING; 43179.ENSSTOP00000015423; -.
DR Ensembl; ENSSTOT00000027010.2; ENSSTOP00000015423.2; ENSSTOG00000024080.2.
DR GeneID; 101977857; -.
DR CTD; 8625; -.
DR eggNOG; KOG0502; Eukaryota.
DR GeneTree; ENSGT00940000160753; -.
DR HOGENOM; CLU_000134_23_0_1; -.
DR InParanoid; I3MTH8; -.
DR OrthoDB; 5477021at2759; -.
DR TreeFam; TF333112; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0045171; C:intercellular bridge; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0042826; F:histone deacetylase binding; IEA:Ensembl.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR017362; DNA-bd_RFXANK.
DR PANTHER; PTHR24124; ANKYRIN REPEAT FAMILY A; 1.
DR PANTHER; PTHR24124:SF4; DNA-BINDING PROTEIN RFXANK; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR PIRSF; PIRSF038034; DNA-binding_RFXANK; 1.
DR SMART; SM00248; ANK; 4.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT REPEAT 119..151
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 152..184
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 185..217
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 256 AA; 27801 MW; 0AF6D57D83BB46C7 CRC64;
MDPTQPAEDL ILTQQSPTPE LGDPEDHGIE TPDGSDTVVL SLFPCTPEPE ADASVCSLQG
SSLKHSTTLT NRQRGNEVSA LPATLDSLSI HQLAAQGELS QLKEHLRKGD NLINKPDERG
FTPLIWASAF GEIETVRFLL EWGADPHILA KERESALSLA SMGGYTDIVG LLLERDVDIN
IYDWNGGTPL LYAVRGNHVK CVEALLARGA DLTTEADSGY TPMDLAVALG YRKVQQVIEN
HILKLFHSNL GPTDPE
//
