ID I3MXM9_ICTTR Unreviewed; 452 AA.
AC I3MXM9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Keratin 80 {ECO:0000313|Ensembl:ENSSTOP00000016874.1};
GN Name=KRT80 {ECO:0000313|Ensembl:ENSSTOP00000016874.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000016874.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000016874.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01037401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005325040.1; XM_005324983.2.
DR AlphaFoldDB; I3MXM9; -.
DR STRING; 43179.ENSSTOP00000016874; -.
DR Ensembl; ENSSTOT00000030137.2; ENSSTOP00000016874.1; ENSSTOG00000024405.2.
DR GeneID; 101967184; -.
DR CTD; 144501; -.
DR eggNOG; ENOG502RVYD; Eukaryota.
DR GeneTree; ENSGT00940000161279; -.
DR HOGENOM; CLU_012560_5_4_1; -.
DR InParanoid; I3MXM9; -.
DR OMA; CSGMEYT; -.
DR OrthoDB; 4640531at2759; -.
DR TreeFam; TF317854; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF1; KERATIN, TYPE II CYTOSKELETAL 80; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 83..394
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 87..163
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 292..372
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 452 AA; 50714 MW; 35095CCD813B49EB CRC64;
MACQSCVVGF SSLSGCEVTP AGSPRPGTSG WGSCGPPVPG FSSRSLTGCW PAGTIPKVTV
NPSLLVPLDL KVDPAIQQQK NQEKEEMKVL NDKFASLIGK VQALEQRNQL LETRWSFLQG
QDSGTFDLGH HYEAYQGRLQ EELRKVSQER GQLEANLLQV LEKVEEFRIR YEDEISKRTD
LEFTFVQLKK DLDAECLRRT ELETKLKGLQ SFMELMRTIY EQEMKDLVAQ VKDVSVTVGM
DSRCHIDLSG IVEEVKAQYD AIAARSLEEA EAYSRSQLEE QAARSAEFGN SLQSSRCEIA
DLNVRIQKLR SQILSVKSHC LKLEENIKAA EEQGELAFQD AKAKLAQLEG ALQQAKQDMA
RQLREYQELM NTKLALDIEI ATYRKLVEGE ESRMDLPSVT VVSAVQSRPR VAASKSLHSK
GSFRKKKNRR GPVIKITEMS EKYLSQESEA SD
//
