ID I3N2B8_ICTTR Unreviewed; 244 AA.
AC I3N2B8;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Electron transfer flavoprotein subunit beta {ECO:0000256|ARBA:ARBA00016797, ECO:0000256|PIRNR:PIRNR000090};
DE Short=Beta-ETF {ECO:0000256|PIRNR:PIRNR000090};
GN Name=ETFB {ECO:0000313|Ensembl:ENSSTOP00000018514.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000018514.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000018514.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: The electron transfer flavoprotein serves as a specific
CC electron acceptor for several dehydrogenases, including five acyl-CoA
CC dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers
CC the electrons to the main mitochondrial respiratory chain via ETF-
CC ubiquinone oxidoreductase (ETF dehydrogenase).
CC {ECO:0000256|PIRNR:PIRNR000090}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta subunit.
CC {ECO:0000256|PIRNR:PIRNR000090}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|ARBA:ARBA00004305, ECO:0000256|PIRNR:PIRNR000090}.
CC -!- SIMILARITY: Belongs to the ETF beta-subunit/FixA family.
CC {ECO:0000256|ARBA:ARBA00007557, ECO:0000256|PIRNR:PIRNR000090}.
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DR EMBL; AGTP01129540; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01129541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3N2B8; -.
DR Ensembl; ENSSTOT00000020684.2; ENSSTOP00000018514.2; ENSSTOG00000006237.3.
DR eggNOG; KOG3180; Eukaryota.
DR GeneTree; ENSGT00390000009936; -.
DR HOGENOM; CLU_015581_0_0_1; -.
DR TreeFam; TF334050; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR CDD; cd01714; ETF_beta; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR000049; ET-Flavoprotein_bsu_CS.
DR InterPro; IPR014730; ETF_a/b_N.
DR InterPro; IPR012255; ETF_b.
DR InterPro; IPR033948; ETF_beta_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR21294; ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT; 1.
DR PANTHER; PTHR21294:SF8; ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA; 1.
DR Pfam; PF01012; ETF; 1.
DR PIRSF; PIRSF000090; Beta-ETF; 1.
DR SMART; SM00893; ETF; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR PROSITE; PS01065; ETF_BETA; 1.
PE 3: Inferred from homology;
KW Electron transport {ECO:0000256|PIRNR:PIRNR000090};
KW Mitochondrion {ECO:0000256|PIRNR:PIRNR000090};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transport {ECO:0000256|PIRNR:PIRNR000090}.
FT DOMAIN 15..207
FT /note="Electron transfer flavoprotein alpha/beta-subunit N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00893"
SQ SEQUENCE 244 AA; 26391 MW; ABE20D5AD7EFBBE1 CRC64;
MITSGPTQIR VKPDKSGVVT DGVKHSMNPF CEIAVEEAVR LKEKKLVKEV IAVSCGPSQC
QETIRTALAM GADRGIHVEV PAAEAERLGP LQVARVLAKL AEKEKVNLVL LGKQAIDDDC
NQTGQMTAGL LDWPQGTFAS QVTLEGDKLK VEREIDGGLE TLRLKLPAVV TADLRLNEPR
YATLPNIMKA KKKKIEVIKA GDLGVDLTSK LSVVSVEDPP QRTAGVKVET TEDLVAKLRE
VGRI
//
