ID I3N562_ICTTR Unreviewed; 580 AA.
AC I3N562;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Solute carrier family 23 member 2-like {ECO:0000313|Ensembl:ENSSTOP00000019508.2};
GN Name=LOC101971424 {ECO:0000313|Ensembl:ENSSTOP00000019508.2};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000019508.2, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000019508.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; AGTP01065868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01065869; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01065870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01065871; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01065872; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01065873; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; I3N562; -.
DR STRING; 43179.ENSSTOP00000019508; -.
DR Ensembl; ENSSTOT00000022748.2; ENSSTOP00000019508.2; ENSSTOG00000025611.2.
DR eggNOG; KOG1292; Eukaryota.
DR GeneTree; ENSGT00950000182953; -.
DR HOGENOM; CLU_017959_5_4_1; -.
DR InParanoid; I3N562; -.
DR TreeFam; TF313272; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF22; SOLUTE CARRIER FAMILY 23 MEMBER 4; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 580 AA; 63614 MW; F1A4340FBC2AF9C0 CRC64;
ELPPVCSFLQ RVDGVLSFHI DDQVTRKDGQ SKSPSSHLAY GVLNIPPWYL CIFLGIQHFL
TALGGMVAVP LILAKDLCLQ HDPLTQSYLI STIFFVSGIC TLLQVLFGVR LLILQGFVAP
SLAMLSLPSW KCPEWTLNAS QVNVSSPEFT EEWQKRIREL QGAIMVASCI QILVGFSGLI
GFLMRFISPL TIAPTISLVA LPLFDPVGND TGIHWGISFT TIFLIMLFSQ FLKNIPVPVP
VYGGEKKCHT SKFYLFQVFP VLLALCISWF ICFVLTVTNT LPSSPTDYGY LARTDTKSNV
LRQAPWFRVP YPGQWGRPTI SLAGVFGIIA GVVSSMVESV GDYYASPPPP KHAINRGIGI
EGLGCLLAGA WGTGNGTTSF SENVGALGIT KVGSRMVIVT AGFVLLLMGV FGKIGAVAVG
ISNLQYVDMN SSRNLFVFGF SIYYGLTIPN WVKKNPEKLQ TGILQLDQVI QVLLTTDMFV
GGFLGFLLDN TIPGSLEERG ILVWNQVQEN SKETTLKSSE VYDFPWGIGT KFCTSSYIRV
LPFWPRLDHS DKGEMGMSQL AHCSHASSRK HLTGAIETRM
//
