ID I3NN34_NOTVI Unreviewed; 305 AA.
AC I3NN34;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE SubName: Full=Homeobox C11 {ECO:0000313|EMBL:ADZ04660.1};
GN Name=HoxC11 {ECO:0000313|EMBL:ADZ04660.1};
OS Notophthalmus viridescens (Eastern newt) (Triturus viridescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Caudata; Salamandroidea; Salamandridae; Pleurodelinae;
OC Notophthalmus.
OX NCBI_TaxID=8316 {ECO:0000313|EMBL:ADZ04660.1};
RN [1] {ECO:0000313|EMBL:ADZ04660.1}
RP NUCLEOTIDE SEQUENCE.
RA Voss S.R., Putta S., Walker J.A., Smith J.J., Maki N., Tsonis P.A.;
RT "Salamander Hox Clusters Contain Repetitive DNA and Expanded Non-Coding
RT Regions: A Typical Hox Structure for Non-Mammalian Tetrapod Vertebrates?";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the Abd-B homeobox family.
CC {ECO:0000256|ARBA:ARBA00006317}.
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DR EMBL; JF490017; ADZ04660.1; -; Genomic_DNA.
DR AlphaFoldDB; I3NN34; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR021918; DUF3528.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR46092; HOMEOBOX PROTEIN HOX-A11-RELATED; 1.
DR PANTHER; PTHR46092:SF1; HOMEOBOX PROTEIN HOX-C11; 1.
DR Pfam; PF12045; DUF3528; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 231..291
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 233..292
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 120..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 171..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 305 AA; 34310 MW; A0587DBE294131E9 CRC64;
MFNSVNLGNF CSQPRKERSA EYGERTNLYL PSCTYYVPEF STVPSFLPQA PSRQISYPYS
SNLSQSVREM PYGLDPGSKW HPRNNYASCY PAAEELMHRE CSLPPSSSMS EMLMKNEGVY
SHHHHRHHHP GANHHPPGSG FYSGIGKNSV LPQGFDRFFD NAYCGGPDPP AAAADEDCAP
KAADPPQPAA AAGDQGLDPE DEEDPSNPGS SASPSSAHNK EGSKGSGSSA PRTRKKRCPY
SKFQIRELER EFFFNVYINK EKRLQLSRML NLTDRQVKIW FQNRRMKEKK LSRDRLQYFS
GNPLL
//
