ID I3RYK5_RALPI Unreviewed; 400 AA.
AC I3RYK5;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Muconate cycloisomerase {ECO:0000313|EMBL:AFK33092.1};
GN ORFNames=p712_0040 {ECO:0000313|EMBL:AFK33092.1};
OS Ralstonia pickettii (Burkholderia pickettii).
OG Plasmid p712 {ECO:0000313|EMBL:AFK33092.1}.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=329 {ECO:0000313|EMBL:AFK33092.1};
RN [1] {ECO:0000313|EMBL:AFK33092.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=712 {ECO:0000313|EMBL:AFK33092.1};
RC PLASMID=p712 {ECO:0000313|EMBL:AFK33092.1};
RA Kim D.-U., Kim M.-S., Ka J.-O.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFK33092.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=712 {ECO:0000313|EMBL:AFK33092.1};
RC PLASMID=p712 {ECO:0000313|EMBL:AFK33092.1};
RX PubMed=23376020; DOI=10.1016/j.plasmid.2013.01.003;
RA Kim D.U., Kim M.S., Lim J.S., Ka J.O.;
RT "Widespread occurrence of the tfd-II genes in soil bacteria revealed by
RT nucleotide sequence analysis of 2,4-dichlorophenoxyacetic acid degradative
RT plasmids pDB1 and p712.";
RL Plasmid 69:243-248(2013).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- PATHWAY: Aromatic compound metabolism. {ECO:0000256|ARBA:ARBA00005211}.
CC -!- SIMILARITY: Belongs to the mandelate racemase/muconate lactonizing
CC enzyme family. {ECO:0000256|ARBA:ARBA00008031}.
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DR EMBL; JQ436722; AFK33092.1; -; Genomic_DNA.
DR RefSeq; WP_011178394.1; NC_019318.1.
DR RefSeq; YP_006963022.1; NC_019318.1.
DR AlphaFoldDB; I3RYK5; -.
DR UniPathway; UPA00083; -.
DR GO; GO:0018850; F:chloromuconate cycloisomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0018849; F:muconate cycloisomerase activity; IEA:InterPro.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR CDD; cd03318; MLE; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR013370; Chloromuconate_cycloisomerase.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR NCBIfam; TIGR02534; mucon_cyclo; 1.
DR PANTHER; PTHR48073:SF2; O-SUCCINYLBENZOATE SYNTHASE; 1.
DR PANTHER; PTHR48073; O-SUCCINYLBENZOATE SYNTHASE-RELATED; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDG01258; (chloro)muconate_cycloisomeras; 1.
DR SFLD; SFLDG00180; muconate_cycloisomerase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00908; MR_MLE_1; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AFK33092.1};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Plasmid {ECO:0000313|EMBL:AFK33092.1}.
FT DOMAIN 165..262
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 400 AA; 42912 MW; 1021F69B5A27976C CRC64;
MLTEKAIADS PNGGDADRKA AQIEAIETVI VDLPLRRIQQ FARLGAKHQS SVLIRLHTKG
GIVGIGESIT PCGPWWSGDS VEAIQATINH YLAPLVVGEP ALDASRIMAK LHGRVAGNAF
AKAGIEMALL DAVGKIVDAP IHVLLGGRFR DRLSVAWPLA TGDVNQEVDE AFRMLEAGKA
GAFKLKMGAL PLAQDLRRAL AIAKELEGKA SLRVDPNEAW DEPTTMRALA PLEAAGVEII
EQPVARWNLD AMARIHRQAR SMLLIDEGVQ SLHDASEVVK RAAAGLVSLK IMKTGGMRPA
RAMADIANAG GMHVYMGTFL ETSIGTAANM QLAASIESLP YGGEVIGPLL IEEDLCEVPA
VYKEHALWLP EGPGLGIRLD ENQVRRFARA SSQRIDRHSA
//
