ID   I3U917_ADVKW            Unreviewed;       286 AA.
AC   I3U917;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=LysR family transcriptional regulator {ECO:0000313|EMBL:AFK61505.1};
GN   OrderedLocusNames=TKWG_04950 {ECO:0000313|EMBL:AFK61505.1};
OS   Advenella kashmirensis (strain DSM 17095 / LMG 22695 / WT001)
OS   (Tetrathiobacter kashmirensis).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae.
OX   NCBI_TaxID=1036672 {ECO:0000313|EMBL:AFK61505.1, ECO:0000313|Proteomes:UP000005267};
RN   [1] {ECO:0000313|EMBL:AFK61505.1, ECO:0000313|Proteomes:UP000005267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17095 / LMG 22695 / WT001
RC   {ECO:0000313|Proteomes:UP000005267};
RX   PubMed=21914874; DOI=10.1128/JB.05781-11;
RA   Ghosh W., George A., Agarwal A., Raj P., Alam M., Pyne P., Das Gupta S.K.;
RT   "Whole-genome shotgun sequencing of the sulfur-oxidizing chemoautotroph
RT   Tetrathiobacter kashmirensis.";
RL   J. Bacteriol. 193:5553-5554(2011).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP003555; AFK61505.1; -; Genomic_DNA.
DR   RefSeq; WP_014749596.1; NC_017964.1.
DR   AlphaFoldDB; I3U917; -.
DR   STRING; 1036672.TKWG_04950; -.
DR   KEGG; aka:TKWG_04950; -.
DR   HOGENOM; CLU_039613_6_5_4; -.
DR   OrthoDB; 9803735at2; -.
DR   Proteomes; UP000005267; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR30126:SF39; RUBISCO TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   286 AA;  31740 MW;  40E769DBD60735C4 CRC64;
     MDTRFLESFV QVVELGSVAA AARQLDLTPT AVSLRLRALE ADVGTALIKR VGRTMMPTEA
     GSKALRQAKL VLAEVKNFNS LASNTELPAG PLTLGATPSV VKGMLPGMLR KWLGKYEGTK
     ILIEPAASTV LYQRLLQGEL DAAILVHPLF EVPKTVLWKQ LRKEPLILLA PARLQGEDPF
     SILRKYPFIR YDRRVVAGKM ADDYLKLHGV YPEPWLELDG LDYISDLVKA DLGVSVVPDW
     SYGNQYDPGL IRHRLPGPVP TRNLGIMWLR SNVREKLIHA FLALAD
//