ID I3VY95_THESW Unreviewed; 494 AA.
AC I3VY95;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=VanW family protein {ECO:0000313|EMBL:AFK87490.1};
GN OrderedLocusNames=Tsac_2492 {ECO:0000313|EMBL:AFK87490.1};
OS Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacterium.
OX NCBI_TaxID=1094508 {ECO:0000313|EMBL:AFK87490.1, ECO:0000313|Proteomes:UP000006178};
RN [1] {ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RA Brown S.D., Land M.L., Herring C.D.;
RT "Thermoanaerobacterium saccharolyticum JW/SL-YS485.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFK87490.1, ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RX PubMed=24907337; DOI=10.1128/AEM.00998-14;
RA Currie D.H., Guss A.M., Herring C.D., Giannone R.J., Johnson C.M.,
RA Lankford P.K., Brown S.D., Hettich R.L., Lynd L.R.;
RT "Profile of Secreted Hydrolases, Associated Proteins, and SlpA in
RT Thermoanaerobacterium saccharolyticum during the Degradation of
RT Hemicellulose.";
RL Appl. Environ. Microbiol. 80:5001-5011(2014).
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DR EMBL; CP003184; AFK87490.1; -; Genomic_DNA.
DR RefSeq; WP_014759322.1; NC_017992.1.
DR AlphaFoldDB; I3VY95; -.
DR STRING; 1094508.Tsac_2492; -.
DR KEGG; tsh:Tsac_2492; -.
DR PATRIC; fig|1094508.3.peg.2527; -.
DR eggNOG; COG2720; Bacteria.
DR BioCyc; TSAC1094508:GLMA-2532-MONOMER; -.
DR Proteomes; UP000006178; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 1.
DR InterPro; IPR011098; G5_dom.
DR InterPro; IPR007391; Vancomycin_resist_VanW.
DR InterPro; IPR022029; YoaR-like_PG-bd.
DR PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR Pfam; PF07501; G5; 1.
DR Pfam; PF12229; PG_binding_4; 1.
DR Pfam; PF04294; VanW; 1.
DR SMART; SM01208; G5; 1.
DR PROSITE; PS51109; G5; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 381..460
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT REGION 464..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 54907 MW; 6434DE6B7FB1E272 CRC64;
METKDTKTIK SKSNYFYIIL LLLIITVFAG SFVMFYSVMN QNTIAKGVFV NGISLSGLTK
SEAYAKLQDN LKAVNNLKVA LKYNDKQFVL PSGDVKISYD YDAIVNEAYS IGKSGNFINR
IKTIYDVSKN GKYLEYRPTA DFNGLDKFVM DISKSIDKNP VDAKIYVSDG KINITNDISG
LKVDANKTIE SIKSAVKSVI ISGDKDYVEI PVTVKEVDAD IKASELSMIK SKIVSFSTQF
NTGDANRSEN LAVAAKAVNG KLLMPGQVFS LNKTLGPRII QNGYKEAPVI IGNKLVPDIG
GGVCQVATTL YNAALRADMK IDERYHHTFP VGYVSPGQDA TISGDVLDLK FENPTKYPIY
IESYISGNNF VVNFYGYSED PGKRIDIYSE IVEKYDPKVT YVDDPTLPEG VTQVDVEKHT
GYKVNTYRLI YENNVLVKKE FLYTDIYKPV DGVIRRGVKK DEVSNNESVQ SQIDEKNVST
EDLNGKPQNI NPTN
//
