ID   I3WFG6_BIFBI            Unreviewed;       440 AA.
AC   I3WFG6;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Putative transport protein {ECO:0000313|EMBL:AFL03629.1};
GN   ORFNames=BBB_0032 {ECO:0000313|EMBL:AFL03629.1};
OS   Bifidobacterium bifidum BGN4.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=484020 {ECO:0000313|EMBL:AFL03629.1, ECO:0000313|Proteomes:UP000006173};
RN   [1] {ECO:0000313|EMBL:AFL03629.1, ECO:0000313|Proteomes:UP000006173}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGN4 {ECO:0000313|EMBL:AFL03629.1,
RC   ECO:0000313|Proteomes:UP000006173};
RX   PubMed=22887663; DOI=10.1128/JB.00988-12;
RA   Yu D.S., Jeong H., Lee D.H., Kwon S.K., Song J.Y., Kim B.K., Park M.S.,
RA   Ji G.E., Oh T.K., Kim J.F.;
RT   "Complete Genome Sequence of the Probiotic Bacterium Bifidobacterium
RT   bifidum Strain BGN4.";
RL   J. Bacteriol. 194:4757-4758(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP001361; AFL03629.1; -; Genomic_DNA.
DR   RefSeq; WP_003815077.1; NC_017999.1.
DR   AlphaFoldDB; I3WFG6; -.
DR   GeneID; 56628269; -.
DR   KEGG; bbf:BBB_0032; -.
DR   PATRIC; fig|484020.3.peg.30; -.
DR   HOGENOM; CLU_015237_4_0_11; -.
DR   Proteomes; UP000006173; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.10.580.10; CBS-domain; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR002550; CNNM.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   PANTHER; PTHR43099:SF5; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF01595; CNNM; 1.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   SMART; SM00116; CBS; 2.
DR   SMART; SM01091; CorC_HlyC; 1.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   PROSITE; PS51371; CBS; 2.
DR   PROSITE; PS51846; CNNM; 1.
PE   4: Predicted;
KW   CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW   ProRule:PRU00703}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000006173};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU01193};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..202
FT                   /note="CNNM transmembrane"
FT                   /evidence="ECO:0000259|PROSITE:PS51846"
FT   DOMAIN          216..276
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
FT   DOMAIN          279..336
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
SQ   SEQUENCE   440 AA;  47706 MW;  C0B83A37C0D58EE2 CRC64;
     MSLGLNILLI FIFLVLGSIF SGTELALVSL RGSQIDQMEQ EDARGARVAA IARDPNKFLS
     TVQIGVTLSG FLSASFGESS ISPFIVPVVK SWGVPANIAA PLTTIVLTLI ISYCSIVISE
     MVPKRIAMQR TEQIARAVVP AIDVFAKVCK PIIWLIGKNT NGIVRLLGFD PNETESEVSD
     EELRVLVNTN TSLSKDERTI LDDVFDASET IVAEVMRPRA DVVFLDGSQS IKDAAAYVRE
     MPYSRYPVTG RDFDDVIGFV HVRDLLDVRD PNATTVADVT REGISLPGTS KLLPSLELLR
     KRGIHLAVVI DEYGGTDGIV TLEDMTEELV GDIRDEYDLP SEPGGERKEQ PAFVSGVATI
     DASMTIEDFA DLTGIELEDG PYETVAGYFL AHTGKMGAEG DVLHSDDGYD MTVTKVDGRR
     IETIEVRKAG APDHAPVSAE
//