ID I3WJ53_BIFBI Unreviewed; 394 AA.
AC I3WJ53;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Cystathionine beta-synthase {ECO:0000313|EMBL:AFL04916.1};
DE EC=4.2.1.22 {ECO:0000313|EMBL:AFL04916.1};
GN Name=cysB {ECO:0000313|EMBL:AFL04916.1};
GN ORFNames=BBB_1324 {ECO:0000313|EMBL:AFL04916.1};
OS Bifidobacterium bifidum BGN4.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=484020 {ECO:0000313|EMBL:AFL04916.1, ECO:0000313|Proteomes:UP000006173};
RN [1] {ECO:0000313|EMBL:AFL04916.1, ECO:0000313|Proteomes:UP000006173}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGN4 {ECO:0000313|EMBL:AFL04916.1,
RC ECO:0000313|Proteomes:UP000006173};
RX PubMed=22887663; DOI=10.1128/JB.00988-12;
RA Yu D.S., Jeong H., Lee D.H., Kwon S.K., Song J.Y., Kim B.K., Park M.S.,
RA Ji G.E., Oh T.K., Kim J.F.;
RT "Complete Genome Sequence of the Probiotic Bacterium Bifidobacterium
RT bifidum Strain BGN4.";
RL J. Bacteriol. 194:4757-4758(2012).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP001361; AFL04916.1; -; Genomic_DNA.
DR AlphaFoldDB; I3WJ53; -.
DR KEGG; bbf:BBB_1324; -.
DR PATRIC; fig|484020.3.peg.1310; -.
DR HOGENOM; CLU_021018_1_0_11; -.
DR Proteomes; UP000006173; Chromosome.
DR GO; GO:0004122; F:cystathionine beta-synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProt.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF194; CYSTATHIONINE BETA-SYNTHASE; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:AFL04916.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000006173}.
FT DOMAIN 66..357
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 394 AA; 42919 MW; DD502F23DB5CCC3B CRC64;
MSHDWHNNIC SRSYNGTAKT NTIIDDHHPP VSTAFNPSAR YTKPNNAPIE TQKETGSTMT
IHNSLSELIG NTPLVKLHHV TDGIKATIAV KVEYFNPGGS SKDRIAERII DAAERSGQLK
PGGVIVEPTS GNTGVGLALV AQQRGYRTIF TLPDKVSESK RAVLRAYGAE VVVTPTDAGP
DDPRSYYQVA ERLANTIPGG FRPNQYDNPN GPLSHYYTTG PEIWEATDHK VTHFVAGIGT
GGTISGTGKY LKEVSDGAVT VVGSDPEGSI YSDPSDVHQY DIEGVGEDFY PKAFDRNITD
DIVQVTDREA FEMTRRLAAE EGLLVGGSSG MAVVSALKYA REHDLDSNQV VVVLLPDSGR
SYLEKIFNDD WMRENGYGDI VERTSRPSLA EQYL
//
