ID I4C3B4_DESTA Unreviewed; 325 AA.
AC I4C3B4;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit {ECO:0000313|EMBL:AFM24055.1};
GN OrderedLocusNames=Desti_1342 {ECO:0000313|EMBL:AFM24055.1};
OS Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1).
OC Bacteria; Thermodesulfobacteriota; Desulfomonilia; Desulfomonilales;
OC Desulfomonilaceae; Desulfomonile.
OX NCBI_TaxID=706587 {ECO:0000313|EMBL:AFM24055.1, ECO:0000313|Proteomes:UP000006055};
RN [1] {ECO:0000313|Proteomes:UP000006055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49306 / DSM 6799 / DCB-1
RC {ECO:0000313|Proteomes:UP000006055};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Zeytun A.,
RA Lu M., Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "Complete sequence of chromosome of Desulfomonile tiedjei DSM 6799.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP003360; AFM24055.1; -; Genomic_DNA.
DR RefSeq; WP_014809206.1; NC_018025.1.
DR AlphaFoldDB; I4C3B4; -.
DR STRING; 706587.Desti_1342; -.
DR KEGG; dti:Desti_1342; -.
DR PATRIC; fig|706587.4.peg.1539; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_7; -.
DR OrthoDB; 9780894at2; -.
DR Proteomes; UP000006055; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Pyruvate {ECO:0000313|EMBL:AFM24055.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006055}.
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 325 AA; 35659 MW; 4F22674FFAE5879C CRC64;
MARLSMVEAI NRTLHELMEQ DDRIVVLGED VGVDGGVFRA TVGLLEKFGP MRVIDTPLAE
STIVGSAIGM AIYGMRPIAE IQFEGFIFKS YDHIYSHASR LRKRSQGGYG VPLVIRAPYG
AGVRALEHHS DAPEALFTHI PGLKLVIPAT PSDAKGLLTS AIEDPDPVIY FEPKRLYRLF
KEEVPEGRHT VPIGQARLVR EGHDITIVTY GGMVSVCEKA AQHVASEGVE AEVIDLRTIW
PFDIGAIVES VTKTGRLIVC HEAPRSFGVG AEIVAQVSER CLLSLLAPIR RVTGNDITAP
LAKLEEYNYP DTEQVVRAIH ETVQF
//
