ID I4CBI4_DESTA Unreviewed; 365 AA.
AC I4CBI4;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=K+ transport system, NAD-binding component {ECO:0000313|EMBL:AFM26925.1};
GN OrderedLocusNames=Desti_4291 {ECO:0000313|EMBL:AFM26925.1};
OS Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1).
OC Bacteria; Thermodesulfobacteriota; Desulfomonilia; Desulfomonilales;
OC Desulfomonilaceae; Desulfomonile.
OX NCBI_TaxID=706587 {ECO:0000313|EMBL:AFM26925.1, ECO:0000313|Proteomes:UP000006055};
RN [1] {ECO:0000313|Proteomes:UP000006055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49306 / DSM 6799 / DCB-1
RC {ECO:0000313|Proteomes:UP000006055};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Zeytun A.,
RA Lu M., Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "Complete sequence of chromosome of Desulfomonile tiedjei DSM 6799.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003360; AFM26925.1; -; Genomic_DNA.
DR RefSeq; WP_014812045.1; NC_018025.1.
DR AlphaFoldDB; I4CBI4; -.
DR STRING; 706587.Desti_4291; -.
DR KEGG; dti:Desti_4291; -.
DR eggNOG; COG1226; Bacteria.
DR HOGENOM; CLU_050982_1_1_7; -.
DR OrthoDB; 9799090at2; -.
DR Proteomes; UP000006055; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR010420; CASTOR/POLLUX/SYM8_dom.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833:SF9; POTASSIUM CHANNEL PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF06241; Castor_Poll_mid; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006055};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..102
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 158..253
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02254"
FT DOMAIN 256..350
FT /note="CASTOR/POLLUX/SYM8 ion channel conserved"
FT /evidence="ECO:0000259|Pfam:PF06241"
SQ SEQUENCE 365 AA; 41072 MW; DA3EA5DAC43D4005 CRC64;
MTFYVLIRKF LVNRKTRRVL LTLGCLFLIL LCSMAGIYYL EQEQSLSLFD SFWLSVVTMT
TVGYGDIAPR THGGRIFMTL VTMICGIGVM AYLVSLIATR VIEREFKTMS GLVDLDCTGH
ILIINCPNEE KVHAIIDELR VDNRSYEVPI VLISDDFPEC PDQLFRRKNF FFVKGNPLLR
RILDRANARE ASQVVILARD PKDGHSDGLT TQVALALENM HRSIGKKLYI AAEAVNRDSV
EPLRTAGVDD VVCLENLVPP IIVQSILDPG IPEVISQLSS KLKEHHFYVG AIPKHAPKLY
GAVRKRLQQG DDLRVIPVGI LRDGKSMVNP PDTLELTEND RLVYIADTRQ WLQDLLVDDT
EANVV
//
