ID I4DHA7_9APIC Unreviewed; 1053 AA.
AC I4DHA7;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Duffy binding protein 1 {ECO:0000313|EMBL:BAM17297.1};
GN Name=dbp1 {ECO:0000313|EMBL:BAM17297.1};
OS Plasmodium cynomolgi.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5827 {ECO:0000313|EMBL:BAM17297.1};
RN [1] {ECO:0000313|EMBL:BAM17297.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Cambodian {ECO:0000313|EMBL:BAM17297.1};
RX PubMed=22863735; DOI=10.1038/ng.2375;
RA Tachibana S., Sullivan S.A., Kawai S., Nakamura S., Kim H.R., Goto N.,
RA Arisue N., Palacpac N.M.Q., Honma H., Yagi M., Tougan T., Katakai Y.,
RA Kaneko O., Mita T., Kita K., Yasutomi Y., Sutton P.L., Shakhbatyan R.,
RA Horii T., Yasunaga T., Barnwell J.W., Escalante A.A., Carlton J.M.,
RA Tanabe K.;
RT "Plasmodium cynomolgi genome sequences provide insight into Plasmodium
RT vivax and the monkey malaria clade.";
RL Nat. Genet. 44:1051-1055(2012).
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DR EMBL; AB617788; BAM17297.1; -; Genomic_DNA.
DR AlphaFoldDB; I4DHA7; -.
DR VEuPathDB; PlasmoDB:PCYB_063270; -.
DR VEuPathDB; PlasmoDB:PcyM_0628800; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR Gene3D; 1.20.58.830; -; 1.
DR Gene3D; 1.20.1310.20; Duffy-antigen binding domain; 1.
DR Gene3D; 1.10.1740.170; Erythrocyte binding antigen 175 region VI; 1.
DR InterPro; IPR042202; Duffy-ag-bd_sf.
DR InterPro; IPR008602; Duffy-antigen-binding.
DR InterPro; IPR021015; Duffy-antigen-binding_C.
DR InterPro; IPR021032; Duffy-antigen-binding_N.
DR InterPro; IPR021620; EBA-175_C.
DR InterPro; IPR043057; EBA-175_C_sf.
DR Pfam; PF12361; DBP; 1.
DR Pfam; PF05424; Duffy_binding; 1.
DR Pfam; PF12377; DuffyBP_N; 1.
DR Pfam; PF11556; EBA-175_VI; 1.
DR SUPFAM; SSF140924; Duffy binding domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1053
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003688224"
FT TRANSMEM 991..1007
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..182
FT /note="Duffy-antigen binding N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12377"
FT DOMAIN 225..425
FT /note="Duffy-antigen binding"
FT /evidence="ECO:0000259|Pfam:PF05424"
FT DOMAIN 537..831
FT /note="Duffy-antigen binding C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12361"
FT DOMAIN 904..982
FT /note="Erythrocyte binding antigen 175 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11556"
FT REGION 112..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..834
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..849
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..869
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1053 AA; 119025 MW; DE04F7F6FAF4CA7C CRC64;
MKGKNRPLFF LLVLLLSHKV NNVLLERTIE TLQECKNEYV KGENCYKLSK GHHYIEEDNI
ERWLQGINER RSEENIKYKY GVTELKIKYE QMNGKRTSRI LKESIYEAQN FRDNNYREEK
DGEHKTDSKT DNGRSANNLV MLDYDTSSSG HPDVTLDNVL EFVTDHGENS LENSSNGGNP
YDIVHKKTMS SGVINHAFLQ NSEIVTCNDK RKRQVRDWDC STKKDVCIPD RRYQLCMKEV
TNLVNNTDTH FHGDITFRKL DFKRKLMYDA AIEGELLYKK NNYKYNKDLC RDIRWSLGDF
GDIIMGTDME GIGHSQVVEN NLRSIFGTGN NALQNRVQWW HESKVHIWRA MMYSVRKRLK
DRFAWICKIN VAVNVEPQIY RWIREWGGDY ITELPTERQK VKEKCDGNII FTKKKVCTVS
QCKNACNLYD QWITRKKEQW DVLSNKFKSV KNEQSIKTAD IATAYDILKQ EINKFNEETF
ENEINKLDNA YIDLCLCSLE EVKKHTQNVV RNVEKAAKSV APNPNPINTA VDSSKTEKVQ
GNPANGNVNS GANNSTTGKA VTGDGQNGNE TPTKSNVQQS DVAESAGAKN VDPQKSVSEK
SADTTSVTSI AEAGKENLGT SNSQPSKSTV EANSPGDGTV NSASISVKNS EKPLVTTDKG
LEPSKDNSDN NGSTESKKSE ANPDSNSKGE TGMGQDNDKE KATKDSSNSS DNTSSAKGDT
TSAVDRNFNG GVPEDRDKIV GSKKEEKEDN SANKDAATVV GGNTNDRTEN GMEKNNVPAP
DSKQSVDATP LSKTESLELN ESAHRITNDT THSLKNENEG SEKDLQKHDF TNNDMPNEDP
NSAQTTDAEG HHRYSMKNDN GEMRKHMNKG TFTKNPNSNQ LNSHNDLSNG KLDIKEYKYR
DVNATREKII YMSEVRRCNN NISLNYCNSV KDKMSSNTCS REKSKNLCCS ISDYCLNYFE
VYTNEYHNCM KKEFEDPSYK CFTKGGFTDK AYFAAGGALL ILLLLITSRH MIKNDSEEAT
FNEFEEHCDN IQRIPLMPNN IEHMQPLTPL DYS
//
