ID I4DJT3_PAPXU Unreviewed; 482 AA.
AC I4DJT3;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=alpha-L-fucosidase {ECO:0000256|ARBA:ARBA00012662};
DE EC=3.2.1.51 {ECO:0000256|ARBA:ARBA00012662};
OS Papilio xuthus (Asian swallowtail butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Papilionidae; Papilioninae; Papilio.
OX NCBI_TaxID=66420 {ECO:0000313|EMBL:BAM18173.1};
RN [1] {ECO:0000313|EMBL:BAM18173.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Epidermis {ECO:0000313|EMBL:BAM18173.1};
RX PubMed=22651552; DOI=10.1186/1741-7007-10-46;
RA Futahashi R., Shirataki H., Narita T., Mita K., Fujiwara H.;
RT "Comprehensive microarray-based analysis for stage-specific larval
RT camouflage pattern-associated genes in the swallowtail butterfly, Papilio
RT xuthus.";
RL BMC Biol. 10:46-46(2012).
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 29 family.
CC {ECO:0000256|ARBA:ARBA00007951, ECO:0000256|PIRNR:PIRNR001092}.
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DR EMBL; AK401551; BAM18173.1; -; mRNA.
DR RefSeq; NP_001299444.1; NM_001312515.1.
DR AlphaFoldDB; I4DJT3; -.
DR GeneID; 106128565; -.
DR OrthoDB; 2955544at2759; -.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR031919; Fucosidase_C.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR Pfam; PF16757; Fucosidase_C; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 2: Evidence at transcript level;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PIRNR:PIRNR001092};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR001092};
KW Signal {ECO:0000256|PIRNR:PIRNR001092}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|PIRNR:PIRNR001092"
FT CHAIN 18..482
FT /note="alpha-L-fucosidase"
FT /evidence="ECO:0000256|PIRNR:PIRNR001092"
FT /id="PRO_5016196051"
FT DOMAIN 377..479
FT /note="Alpha-L-fucosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16757"
SQ SEQUENCE 482 AA; 55961 MW; 3B9699DA968E7D24 CRC64;
MKILLLCILV LCSVVSSYST VESGESRHIS GHLVSKKYSP DWKDLDTRPL PHWYDDAKIG
IFLHWGVYSV IGFSEWFWSN WKGGDKKITK FMKEHYPPDF TYQDFAPMFK AEFFDPTEWA
DLFLKSGARY IVLTSKHHDG FTMFPSHRSY SWNSYEVGPK RDIVGELSTA VRAAGLKFGV
YHSLYEWFNP IYEEDKKNNF TTRYYAETKL WPDLKQLIND YKPSVLWSDG DWETYDTYWK
STDFLAWLYN ESPVKDEIVV NDRWGIGIPC KHGDFYNCAD RYNPGSLQNH KWENAFTVDS
RSWGFRKPMT LNDTLSTNQI LYQVVSTISC GGNALINVGP TQDGTISPIF QERLLDLGNW
LKINGEAIYS TSPWLHQNDS LNQDVWYTCR KVKHSHRHPT AIPRDNDNII AIYAIFLKWP
TTNILLLKDL STYLHNGVYK IELLGNEGLI NWNIKNGVTS IELPDKAKVH SENAWTLKMS
LK
//
