ID I4EAY3_METSZ Unreviewed; 263 AA.
AC I4EAY3;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Type IV secretion system protein virB8 {ECO:0000256|ARBA:ARBA00014420};
GN Name=virB8 {ECO:0000313|EMBL:CCD32139.1};
GN OrderedLocusNames=SC2p1_02240 {ECO:0000313|EMBL:CCD32139.1};
OS Methylocystis sp. (strain SC2).
OG Plasmid pBSC2-1 {ECO:0000313|Proteomes:UP000005263}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylocystaceae; Methylocystis.
OX NCBI_TaxID=187303 {ECO:0000313|EMBL:CCD32139.1, ECO:0000313|Proteomes:UP000005263};
RN [1] {ECO:0000313|Proteomes:UP000005263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2 {ECO:0000313|Proteomes:UP000005263};
RC PLASMID=pBSC2-1 {ECO:0000313|Proteomes:UP000005263};
RX PubMed=23045511; DOI=10.1128/JB.01446-12;
RA Dam B., Dam S., Kube M., Reinhardt R., Liesack W.;
RT "Complete Genome Sequence of Methylocystis sp. Strain SC2, an Aerobic
RT Methanotroph with High-Affinity Methane Oxidation Potential.";
RL J. Bacteriol. 194:6008-6009(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the virB8 family.
CC {ECO:0000256|ARBA:ARBA00011070}.
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DR EMBL; FO000001; CCD32139.1; -; Genomic_DNA.
DR AlphaFoldDB; I4EAY3; -.
DR Proteomes; UP000005263; Plasmid pBSC2-1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR CDD; cd16424; VirB8; 1.
DR Gene3D; 3.10.450.230; VirB8 protein; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR007430; VirB8.
DR InterPro; IPR026264; VirB8/PtlE.
DR Pfam; PF04335; VirB8; 1.
DR PIRSF; PIRSF003299; VirB8_PtlE; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT TRANSMEM 39..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..238
FT /note="Bacterial virulence protein VirB8"
FT /evidence="ECO:0000259|Pfam:PF04335"
SQ SEQUENCE 263 AA; 29326 MW; 4DB93D12AB2ABBE0 CRC64;
MQIEAGNGVD QPLVNESYFH DGARWERDIY RRLEISRNVW RVVAVAALIC LAIGLLTLLS
LVPLKSTEVV TLLVDKATGF VEVAKPLEEG GPISQREAVT QANIVRYIRA RETYDPPALR
DNFELASLLS AGQASKDLQE AFSPNNLHNP VKLYGINGRI RVIVHSVNFL SQGWMENPKS
PATAAVRFTS VRTSDRERME EHWAANVRFR YTAEPMKNEW RWDNPLGFQV IEYRKDQETV
APIVGAAPVE APTVAPPTGA PAP
//
