ID I4LWJ5_GARVA Unreviewed; 404 AA.
AC I4LWJ5;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=MutT1 protein {ECO:0000313|EMBL:EIK81335.1};
GN ORFNames=CGSMWGv55152_00670 {ECO:0000313|EMBL:EIK81335.1};
OS Gardnerella vaginalis 55152.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=698955 {ECO:0000313|EMBL:EIK81335.1, ECO:0000313|Proteomes:UP000005936};
RN [1] {ECO:0000313|EMBL:EIK81335.1, ECO:0000313|Proteomes:UP000005936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=55152 {ECO:0000313|EMBL:EIK81335.1,
RC ECO:0000313|Proteomes:UP000005936};
RX PubMed=22609915; DOI=10.1128/JB.00056-12;
RA Ahmed A., Earl J., Retchless A., Hillier S., Rabe L., Cherpes T.,
RA Powell E., Janto B., Eutsey R., Hiller N.L., Boissy R., Dahlgreen M.,
RA Hall B., Costerton J., Post J.C., Hu F., Ehrlich G.;
RT "Comparative Genomic Analyses of 17 Clinical Isolates of Gardnerella
RT vaginalis Provide Evidence of Multiple Genetically Isolated Clades
RT Consistent with Subspeciation into Genovars.";
RL J. Bacteriol. 194:3922-3937(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIK81335.1}.
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DR EMBL; ADEQ01000002; EIK81335.1; -; Genomic_DNA.
DR AlphaFoldDB; I4LWJ5; -.
DR PATRIC; fig|698955.3.peg.128; -.
DR Proteomes; UP000005936; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03673; Ap6A_hydrolase; 1.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR020084; NUDIX_hydrolase_CS.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR21340; DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT; 1.
DR PANTHER; PTHR21340:SF8; NUDIX HYDROLASE; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF00293; NUDIX; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS51462; NUDIX; 1.
DR PROSITE; PS00893; NUDIX_BOX; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 9..192
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
FT REGION 309..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 404 AA; 45549 MW; 6D14655BE3F35911 CRC64;
MNMSVVTTRY VEAAGGIIYR KRNTIDSSNT SDLKKTSNQA SMISDDDFEL CLVYRPKYDD
WSWPKGKNED NESHRHTAVR EVGEETGYAV TLGPHIAQIE YPLENEGKKS ISKSGAKNSS
QNNNKTEVVK RIHYWMMREI DENSAMRRLP AFGPIKPAKP TEIGNVIWLT PSKARKKLTH
DSDRKVLDAF LEKLHACQTE YKTLILVRHG KAESRKSWQG SEATRPITPL GSAASYALGR
ELACYAPNRI VSSPWKRCVE TVATFAHDSS LPIEQIAELT EDHHENKPKS TLSVLISEIQ
NLDCNVKNTQ NTQNTQNTQN TQNTQNTQNA EENINNSTVM CLHRPIIGTF FDYLRGITKP
RAHKRILSQK SPYMPTGSAI VLHISNTSKG ARIIDIEKVL PIVY
//
