ID I4MDN3_GARVA Unreviewed; 596 AA.
AC I4MDN3;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Choline/ethanolamine kinase {ECO:0000313|EMBL:EIK87323.1};
GN ORFNames=CGSMWGv6119V5_03444 {ECO:0000313|EMBL:EIK87323.1};
OS Gardnerella vaginalis 6119V5.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=698961 {ECO:0000313|EMBL:EIK87323.1, ECO:0000313|Proteomes:UP000033041};
RN [1] {ECO:0000313|EMBL:EIK87323.1, ECO:0000313|Proteomes:UP000033041}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6119V5 {ECO:0000313|EMBL:EIK87323.1,
RC ECO:0000313|Proteomes:UP000033041};
RX PubMed=22609915; DOI=10.1128/JB.00056-12;
RA Ahmed A., Earl J., Retchless A., Hillier S., Rabe L., Cherpes T.,
RA Powell E., Janto B., Eutsey R., Hiller N.L., Boissy R., Dahlgreen M.,
RA Hall B., Costerton J., Post J.C., Hu F., Ehrlich G.;
RT "Comparative Genomic Analyses of 17 Clinical Isolates of Gardnerella
RT vaginalis Provide Evidence of Multiple Genetically Isolated Clades
RT Consistent with Subspeciation into Genovars.";
RL J. Bacteriol. 194:3922-3937(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIK87323.1}.
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DR EMBL; ADEW01000007; EIK87323.1; -; Genomic_DNA.
DR RefSeq; WP_004136724.1; NZ_ADEW01000007.1.
DR AlphaFoldDB; I4MDN3; -.
DR PATRIC; fig|698961.3.peg.676; -.
DR eggNOG; COG0510; Bacteria.
DR eggNOG; COG1846; Bacteria.
DR eggNOG; COG4750; Bacteria.
DR OrthoDB; 179763at2; -.
DR Proteomes; UP000033041; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05151; ChoK-like; 1.
DR CDD; cd02523; PC_cytidylyltransferase; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR025877; MobA-like_NTP_Trfase.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43584; NUCLEOTIDYL TRANSFERASE; 1.
DR PANTHER; PTHR43584:SF5; PROTEIN LICC; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF12804; NTP_transf_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EIK87323.1};
KW Transferase {ECO:0000313|EMBL:EIK87323.1}.
FT DOMAIN 77..169
FT /note="MobA-like NTP transferase"
FT /evidence="ECO:0000259|Pfam:PF12804"
SQ SEQUENCE 596 AA; 68468 MW; AF58BBC3BF2C3E8B CRC64;
MAINHNEFRL LTALLNNTNN SQQISQRDIA TRAGISLGTV NSAIKSAENK HLIKAAETLQ
ITPKGLAELE PHKVKNAIIM AAGFSSRFSP VSYETPKGLL TVKGEVLIER QIKQLHEAGI
NDITVVVGYK QEQFFYLEDA FNVKIVPNSE YNTRNNNSSL MAVANQLSNT YICSSDNYFD
ENPFEKYVWK AYYSAQFQQG YTKEWCMTCG AHNRITKVTI GGSDAWYMIG HVYFDTEFSK
RFVQILRKEY DLPQTAGKLW EDIFIEHIDE LDMQMRKYDP PIIHEFDSID ELREFDPLFL
ENIDSAIFDH ITQTLNCKKS DIYNVYPLKN GLTNLSCHFS VGKSEYVYRH PGVGTDVLIN
RKAEVEALNL AKQIGLDGTF IAADETVGWK ISHFLPDCKT ANMHDLKELK EGLALVRLLH
ESNRKMLRTF DFYLESQRYI SELNNRKVTI PQKIIDLGLS AKKLHELVVS KDSQNYCPCH
NDVLGANILI DKQNRYHLID WEYAGMSDYA QDFGTLCVSD EFSDTEINEA MPIYLAHTPS
TQEKRHLLAF VGFAGWCWHL WSLVKEAEGE NIGTCMYTYY RYAKRYINEA LKMYEN
//
