ID I4YIC8_WALMC Unreviewed; 416 AA.
AC I4YIC8;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=(2E,6E)-farnesyl diphosphate synthase {ECO:0000256|ARBA:ARBA00032873};
DE AltName: Full=Dimethylallyltranstransferase {ECO:0000256|ARBA:ARBA00032448};
DE AltName: Full=Farnesyl diphosphate synthase {ECO:0000256|ARBA:ARBA00032424};
DE AltName: Full=Farnesyltranstransferase {ECO:0000256|ARBA:ARBA00032052};
DE AltName: Full=Geranylgeranyl diphosphate synthase {ECO:0000256|ARBA:ARBA00033096};
DE AltName: Full=Geranyltranstransferase {ECO:0000256|ARBA:ARBA00032380};
GN ORFNames=WALSEDRAFT_59360 {ECO:0000313|EMBL:EIM23720.1};
OS Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) (Wallemia sebi (CBS
OS 633.66)).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=671144 {ECO:0000313|EMBL:EIM23720.1, ECO:0000313|Proteomes:UP000005242};
RN [1] {ECO:0000313|EMBL:EIM23720.1, ECO:0000313|Proteomes:UP000005242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4683 / CBS 633.66 {ECO:0000313|Proteomes:UP000005242};
RX PubMed=22326418; DOI=10.1016/j.fgb.2012.01.007;
RA Padamsee M., Kumar T.K.A., Riley R., Binder M., Boyd A., Calvo A.M.,
RA Furukawa K., Hesse C., Hohmann S., James T.Y., LaButti K., Lapidus A.,
RA Lindquist E., Lucas S., Miller K., Shantappa S., Grigoriev I.V.,
RA Hibbett D.S., McLaughlin D.J., Spatafora J.W., Aime M.C.;
RT "The genome of the xerotolerant mold Wallemia sebi reveals adaptations to
RT osmotic stress and suggests cryptic sexual reproduction.";
RL Fungal Genet. Biol. 49:217-226(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; JH668224; EIM23720.1; -; Genomic_DNA.
DR RefSeq; XP_006956385.1; XM_006956323.1.
DR AlphaFoldDB; I4YIC8; -.
DR STRING; 671144.I4YIC8; -.
DR GeneID; 18473311; -.
DR KEGG; wse:WALSEDRAFT_59360; -.
DR eggNOG; KOG0776; Eukaryota.
DR HOGENOM; CLU_014015_1_0_1; -.
DR InParanoid; I4YIC8; -.
DR OMA; AFDYYLH; -.
DR OrthoDB; 25272at2759; -.
DR Proteomes; UP000005242; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR GO; GO:1901663; P:quinone biosynthetic process; IEA:UniProt.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000005242};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 416 AA; 44950 MW; 5CB80A63FCBDE4DD CRC64;
MFNRKAASIA ARPVRGYSWT TAASLAKAAA THKASSPISV DPFTLVGKEL KGLTGSIKLN
LGSNLKSLDT LSKYYFEAQG KHLRPTIVLL MAQATAGLSP HYNASKDLKN VLVNDPLAPQ
SILNDNNPSF HNGISHIGQD GILATQRRLA EIVEMIHVAS LLHDDVVDDA DTRRGAPSAP
VKFGNKLTIF AGDFLLGRAS IMLARLRSLE VAELIGATIA NLVEGEVAQL NETYESKSTN
TETIIDEAFE RYLSKTYLKT ASLISSSSRA AVCLGGVGIN ENWPEGEYLK DAAYEYGRNL
GMAFQLVDDL LDYTSSVDLG KPGEGADMQL GLATAPALFA WREFEEIGPL IKRKFKHPGD
VQVAKEIVAN SQGMPKTAEL AASYIDKAKI ALHKLPESEA RDGLEALCLK VLDRVK
//
