ID I5C9A2_9BACT Unreviewed; 736 AA.
AC I5C9A2;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Glutamate carboxypeptidase II {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3SI_04030 {ECO:0000313|EMBL:EIM78404.1};
OS Nitritalea halalkaliphila LW7.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Nitritalea.
OX NCBI_TaxID=1189621 {ECO:0000313|EMBL:EIM78404.1, ECO:0000313|Proteomes:UP000005551};
RN [1] {ECO:0000313|EMBL:EIM78404.1, ECO:0000313|Proteomes:UP000005551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LW7 {ECO:0000313|EMBL:EIM78404.1,
RC ECO:0000313|Proteomes:UP000005551};
RA Jangir P.K., Singh A., Shivaji S., Sharma R.;
RT "Genome sequence of Nitritalea halalkaliphila LW7.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIM78404.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJYA01000007; EIM78404.1; -; Genomic_DNA.
DR AlphaFoldDB; I5C9A2; -.
DR STRING; 1189621.A3SI_04030; -.
DR PATRIC; fig|1189621.3.peg.842; -.
DR Proteomes; UP000005551; Unassembled WGS sequence.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005551}.
FT DOMAIN 183..247
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 368..552
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 617..725
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
SQ SEQUENCE 736 AA; 81741 MW; 3D54C1A4F064968D CRC64;
MAQPKKAFPP DHLHKKRGHF LFNPYLGLFN KESYSMKKKY LYGLGLCMAL HLPILQAQTL
NGFSTEKQKQ QESLEKRFLD LVDESGFRRH LEILTKEPHP AGSEANKRVE AYMAETMQAA
GWEVKRYPYD VYLSKEPGTS LIEIIRPNRE PLSQQENEWE ADPYLAHPDL GKGWNAFSGS
GDVRGEVVYV NYGVKADFEA LKKMGVDLKG KILLARYGGN FRGFKAKFAE EAGAAGLIIY
TDPKDSGFTR GLTYPEGIFY DASAIQRGSL LTVPWTGDAL TPFKPALPRD GKQKVDRLDP
ETEGLLHSIP VLPIGYGAAE KILSQMKGQA VPPAWQGGLP FTYRIEGGSG LEVRVMVDQK
REFVRATNVV GTLKGSKYPD EWIILGCHYD AWSFGSTDPN SGTALLLNLS ETLQKLAQEG
YRPERSILIA HWDAEEHGVI GSTEWVEQLH DELQAKALAY INLDAAVSGR NFGAASSPTL
KQGIIEAAKM VTFPDSAKTV FEVWAGQKEE PTIGNLGGGS DHIAFYMHAG IPSLSGGASG
PTLYHTNYDN MHFYETFADP SFKMGAAVER LVGILTLRLA NADVIPYQVS RYAQDLEGHF
QTATRQVQSF DKGFEGFPQV RAALEALTAK GQAWDSAVEK ALATGSLKPD QLKTINKQLL
GLEKSFIDKK GMYFGDWYRS LYASNDPFSG YASWILPGIQ YEVERKSTER LAEWDTRYAA
ALDDLRQKID ALLELL
//
