ID I6AR39_9BACT Unreviewed; 1103 AA.
AC I6AR39;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:EIP97480.1};
GN ORFNames=OpiT1DRAFT_01920 {ECO:0000313|EMBL:EIP97480.1};
OS Opitutaceae bacterium TAV1.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=278956 {ECO:0000313|EMBL:EIP97480.1, ECO:0000313|Proteomes:UP000004921};
RN [1] {ECO:0000313|EMBL:EIP97480.1, ECO:0000313|Proteomes:UP000004921}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAV1 {ECO:0000313|EMBL:EIP97480.1,
RC ECO:0000313|Proteomes:UP000004921};
RX PubMed=22535930; DOI=10.1128/JB.00264-12;
RA Isanapong J., Goodwin L., Bruce D., Chen A., Detter C., Han J., Han C.S.,
RA Held B., Huntemann M., Ivanova N., Land M.L., Mavromatis K., Nolan M.,
RA Pati A., Pennacchio L., Pitluck S., Szeto E., Tapia R., Woyke T.,
RA Rodrigues J.L.;
RT "High-Quality Draft Genome Sequence of the Opitutaceae Bacterium Strain
RT TAV1, a Symbiont of the Wood-Feeding Termite Reticulitermes flavipes.";
RL J. Bacteriol. 194:2744-2745(2012).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; JH660698; EIP97480.1; -; Genomic_DNA.
DR AlphaFoldDB; I6AR39; -.
DR HOGENOM; CLU_003442_0_1_0; -.
DR Proteomes; UP000004921; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR Gene3D; 2.60.40.2220; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 534..617
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1103 AA; 122785 MW; A927E53FA01268B1 CRC64;
MSLNTEWRPR VEAWIKALDQ LVYAPVAPLA LEAFFTYDQL TADEAMCRAF SPIAPGTRWG
AKWQYAWFRG QIPPLPPSPE TNEHSVLHAG HPTPQFGGDM FGEWRVFIDG AEIGSRDWAH
VYLPVARAFS ANRPHSSTPA GGTPAPLQFL AEAFGGPTRA GAGGGPALHG VPTLPEPPPQ
QRILPDVTAG LWREDIFQLA MDARTLLDLR DQLDSDSLRV AEIDAGLRDF TLIADPELPW
PEMRPTLLRA RERLAPLLAC RNGTTAPTLF CIGHSHLDIV YQWPLKEAER KVARTFANQL
GLMEQYPEYR YLQSMPVLYE IAKRLHPRLY ARVKEAVRRG QWIPEGAMWT EADTNLPGGE
SLIRQFLYGR RFFRDEFGVE STFAWLPDTF GFTGSLPQIM AGCGIGHFGS SKLFTVFAEE
GDPFPYTTFW WEGIDGTRVL SHFVPSYGIM TNPRSIDAQW KQNPQKDGIR ARMAVYGHSD
GGGGCERAHL EYLRRLADLE GAPRCRHATP AEFFEYQEKQ PDPLPAWTGE IYLPAHRGCY
TTQAALKRGN RRCEMMLREA ELWSAVAYIF TRRASSPQAW PRAALETAWK KTLFNQFHDI
LPGSCIERAA QEAREFHDES LAEATAVANT AMAVLSEWHG LPARPVSQAS SPSGPQTADA
TPVPRQSALL FNSLAWPRTE LVALPPAFPA DALPPATPTL RLDGATWVSA TVPACGWTDL
ATAVTPLADP SVRSDRSPPA SSLILENTPY RLVLDQLGRI TSWHDKATGR ELAAAPLNDF
RMYRDTPRVC DAWEIESHYA RQPVDLTPPA ATPATVELLS DGPLATVLRI RRRLHDSDLD
QEIRLARNSR RIEFRTRIRW HEKHKLLKVA FPLALTAHEA LHEIQFGHLR RPTHRSRKAD
RDRFEVCQQK WSALAEENRG VALLNDGKHG ISAEQNTLAL TLLRAPQAPD MHADLGDHEF
TYALYAWDGP FAGSGVTQAA LELNAPLRFA PDIRPPDVRH STPDAGCSGV SLFSCDAPNI
ILETVKLAED DSGDLVLRLY ESARAATRCH LRIDLAATSF HSACETDMLE NPLSGRALPL
PDAAGLGLDF RPFEIKTLRL RPA
//
